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  1. Article

    Open Access

    Pharmacokinetics of thiotepa in high-dose regimens for autologous hematopoietic stem cell transplant in Japanese patients with pediatric tumors or adult lymphoma

    Thiotepa is used in high-dose chemotherapy (HDT) before autologous hematopoietic stem cell transplantation (HSCT) to treat solid tumors and hematological malignancies. This Phase 1 study was conducted to estab...

    Eisei Kondo, Takashi Ikeda, Hiroaki Goto… in Cancer Chemotherapy and Pharmacology (2019)

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  2. Article

    Discovery of 4-Pyridone Derivatives as Specific Inhibitors of Enoyl-Acyl Carrier Protein Reductase (FabI) with Antibacterial Activity against Staphylococcus aureus

    4-Pyridone derivatives were identified as potent inhibitors of FabI, the enoyl-acyl carrier protein reductase in Escherichia coli and Staphylococcus aureus. 1-Substituted derivatives of a hit compound exhibited p...

    Sho Takahata, Maiko Iida, Takuji Yoshida, Ko Kumura… in The Journal of Antibiotics (2007)

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  3. No Access

    Article

    Effects of prestrain on the fracture properties of pressure vessel steel

    In this paper, various methods have been used to measure the effects of prestrain on the fracture toughness of 20 g steel experimentally. Based on elastic-plastic FEM analysis, the relationships between crack ...

    Zhu Hanxing, Li Guangxia, Li Changchun, Hideo Kitagawa in International Journal of Fracture (1992)

  4. No Access

    Article

    Effects of prestrain on the crack rotational factor for pressure vessel steels

    Zhu Hanxing, Hideo Kitagawa, Li Changchun, Li Guangxia in International Journal of Fracture (1992)

  5. No Access

    Chapter

    Diffusion of Hydrogen Near an Elasto-Plastically Deformed Crack Tip

    The mechanism of hydrogen embrittlemnt(HE) of high strength steels at room temperature has been discussed, with no unified consensus on understanding of its phenomenon itself nor the method of its quantitative...

    Hideo Kitagawa, Yukio Kojima in Atomistics of Fracture (1983)

  6. No Access

    Article

    Activities in experimental stress and strain analysis in some asian countries

    Paper discusses the recent activities in the experimental stress and strain analysis (ESSA) fields in Asia, referring the information from Japan, Korea, China and India, for example. It includes a general view...

    Hideo Kitagawa in Experimental Mechanics (1981)

  7. No Access

    Article

    Invariability, hesitation or restoration of damage in wet-dry fatigue process

    The effects of corrosive wet conditions on the progress of fatigue were studied by means of wet-dry two-stage tests of same stress level. Some results from the two-state tests—invariability, hesitation, etc., ...

    Hideo Kitagawa in Experimental Mechanics (1967)