Transactions on Engineering Technologies
International MultiConference of Engineers and Computer Scientists 2021
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Article
Open AccessInvestigating the cut-off values of captopril challenge test for primary aldosteronism using the novel chemiluminescent enzyme immunoassay method: a retrospective cohort study
The measurement evolution enabled more accurate evaluation of aldosterone production in hypertensive patients. However, the cut-off values for novel assays have been not sufficiently validated. The present stu...
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Article
Open AccessAuthor Correction: Optogenetic stimulation of vagal nerves for enhanced glucose-stimulated insulin secretion and β cell proliferation
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Article
Open AccessA Multicenter, Open-Label, Single-Arm Trial of the Efficacy and Safety of Empagliflozin Treatment for Refractory Diabetes Mellitus with Insulin Resistance (EMPIRE-01)
Insulin resistance syndrome and lipoatrophic diabetes are characterized by severe insulin resistance and are often refractory to treatment. Trials assessing the efficacy of antidiabetes drugs for these rare co...
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Article
Open AccessInter-organ communication involved in metabolic regulation at the whole-body level
Metabolism in each organ of multi-organ organisms, including humans, is regulated in a coordinated manner to dynamically maintain whole-body homeostasis. Metabolic information exchange among organs/tissues, i....
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Article
Open AccessOptogenetic stimulation of vagal nerves for enhanced glucose-stimulated insulin secretion and β cell proliferation
The enhancement of insulin secretion and of the proliferation of pancreatic β cells are promising therapeutic options for diabetes. Signals from the vagal nerve regulate both processes, yet the effectiveness o...
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Article
Open AccessA highly sensitive strategy for monitoring real-time proliferation of targeted cell types in vivo
Cell proliferation processes play pivotal roles in timely adaptation to many biological situations. Herein, we establish a highly sensitive and simple strategy by which time-series showing the proliferation of...
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Chapter and Conference Paper
Scheduling Algorithm Using Path Relinking in Different Search Paths for Production Process with Crane Interference
The importance of production planning systems that respond to customer requirements for smaller lot sizes, higher quality, and shorter delivery times in response to the increased variety of products is growing...
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Book and Conference Proceedings
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Article
Open AccessInsulin-like growth factor-1 levels are associated with high comorbidity of metabolic disorders in obese subjects; a Japanese single-center, retrospective-study
Insulin like growth factor-1 (IGF-1) plays important roles in metabolic functions, especially in adulthood. Additionally, obese subjects are reportedly predisposed to having low absolute IGF-1 levels. However,...
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Article
New classification and diagnostic criteria for insulin resistance syndrome
This report of a working group established by the Japan Diabetes Society proposes a new classification and diagnostic criteria for insulin resistance syndrome. Insulin resistance syndrome is defined as a condi...
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Chapter and Conference Paper
Machine Learning Methods for Detecting Wiring Defects of Glass Substrates Through Non-contact Line Scanning Data
This paper focuses on defect detection of glass substrates since the demand for ultra-high definition with 4 K and 8 K panels has recently increased. A fast algorithm for detecting wiring defects of glass subs...
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Article
Open AccessExtraordinarily long-inactive solitary fibrous tumor transformed to produce big insulin-like growth factor-2, leading to hypoglycemia and rapid liposarcoma growth: a case report
A high-molecular-weight form of insulin-like growth factor-2 (IGF-2), known as “big” IGF-2, is occasionally produced by various tumor types, leading to hypoglycemia. Although solitary fibrous tumor (SFT) is a ...
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Article
Diabetes care providers’ manual for disaster diabetes care
To ensure that experiences and lessons learned from the unprecedented 2011 Great East Japan Earthquake are used to improve future disaster planning, the Japan Diabetes Society (JDS) launched the “Research and ...
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Article
Open AccessEnhancement of postprandial endogenous insulin secretion rather than exogenous insulin injection ameliorated insulin antibody-induced unstable diabetes: a case report
Insulin injection, especially with insulin analogs, occasionally induces the production of insulin antibodies with high binding capacity and low affinity, similar to the insulin autoantibodies characteristic o...
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Article
Open AccessVagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation
The liver possesses a high regenerative capacity. Liver regeneration is a compensatory response overcoming disturbances of whole-body homeostasis provoked by organ defects. Here we show that a vagus-macrophage...
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Article
Glial Fatty Acid-Binding Protein 7 (FABP7) Regulates Neuronal Leptin Sensitivity in the Hypothalamic Arcuate Nucleus
The hypothalamus is involved in the regulation of food intake and energy homeostasis. The arcuate nucleus (ARC) and median eminence (ME) are the primary hypothalamic sites that sense leptin and nutrients in th...
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Article
Open AccessSelective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers
Insulin signals, via the regulation of key enzyme expression, both suppress gluconeogenesis and enhance lipid synthesis in the liver. Animal studies have revealed insulin signaling favoring gluconeogenesis sup...
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Article
Myriad mysteries of glucose homeostasis
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Article
Open AccessOlfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion
Olfactory receptors (ORs) mediate olfactory chemo-sensation in OR neurons. Herein, we have demonstrated that the OR chemo-sensing machinery functions in pancreatic β-cells and modulates insulin secretion. Firs...
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Article
Open AccessNeuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism
Under insulin-resistant conditions such as obesity, pancreatic β-cells proliferate to prevent blood glucose elevations. A liver–brain–pancreas neuronal relay plays an important role in this process. Here, we s...
