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Article
Open AccessPossible roles of anti-type II collagen antibody and innate immunity in the development and progression of diabetic retinopathy
The pathogenesis of both diabetic retinopathy (DR) and rheumatoid arthritis (RA) has recently been considered to involve autoimmunity. Serum and synovial fluid levels of anti-type II collagen antibodies increa...
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Article
Impact of habitual swimming on the success of lacrimal surgery
To elucidate how factors associated with swimming affect the lacrimal ducts of swimmers.
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Article
Open AccessHyperglycemia-induced VEGF and ROS production in retinal cells is inhibited by the mTOR inhibitor, rapamycin
Determine the impact of the mTOR inhibitor, rapamycin, on the hyperglycemia-induced expression of vascular endothelial growth factor (VEGF) and the production of reactive oxygen species (ROS) in retinal cells....
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Article
Correction to: Significant correlations between photopic negative response, afferent pupillary defect, and mean defects of visual fields in asymmetric optic nerve disorders
The original publication of this paper contains mistakes.
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Article
Significant correlations between photopic negative response, afferent pupillary defect, and mean defects of visual fields in asymmetric optic nerve disorders
The photopic negative response (PhNR) is a negative wave following the b-wave of the photopic electroretinogram (ERG). The PhNR originates from the retinal ganglion cells (RGCs), and it can be used to assess t...
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Article
Investigation of scleral thermal injuries caused by ultrasonic pars plana phacoemulsification and aspiration using pig eyes
The purpose of this study was to investigate the thermal injuries caused by ultrasonic pars plana phacoemulsification and aspiration (PPPEA) using pig eyes.
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Article
Protein kinase C-mediated insulin receptor phosphorylation in diabetic rat retina
Diabetic retinopathy (DR) involves a proliferation of vascular endothelial cells and loss of pericytes. There is a link among the action of protein kinase C (PKC) and insulin signaling. Thus, we investigated t...
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Article
Open AccessImmunohistological Study of Monkey Foveal Retina
The fovea centralis, an anatomically concave pit located at the center of the macula, is avascular, hypoxic, and characteristic of stem-cell niches of other tissues. We hypothesized that in the fovea, undiffer...
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Article
Open AccessDevelopment of macular retinoschisis long after the onset of retinal arterial occlusion (RAO): a retrospective study
To describe a retrospective study of macular retinoschisis that developed long after the onset of retinal artery occlusion (RAO) using optical coherence tomography (OCT).
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Article
Implication of VEGF and aquaporin 4 mediating Müller cell swelling to diabetic retinal edema
Aquaporin 4 (AQP4), a water channel protein, is known to be expressed in retinal Müller cells. The purpose of this study was to determine the effects of VEGF and AQP4 channels on the volumetric changes in Müll...
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Article
Protective effect of P7C3 on retinal ganglion cells from optic nerve injury
To determine whether P7C3-A20, a proneurogenic neuroprotective agent, can protect the retinal ganglion cells (RGCs) of rats from optic nerve crushing.
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Article
Comparison of histopathological findings between idiopathic and secondary epiretinal membranes
To evaluate the histopathological findings of idiopathic and secondary epithelial membranes (ERMs). This study involved 19 ERM cases that underwent pars plana vitrectomy (PPV). ERM specimens were obtained from...
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Article
Expression of a hyaluronic acid-binding proteoglycan (versican) in the cynomolgus monkey eye
The expression of versican, a hyaluronic acid (HA)-binding protein, during the development and differentiation of the retina has been reported. In this study, we performed histochemical and immunohistological ...
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Article
Open AccessSuppressed endothelin-1 by anti-VEGF therapy is important for patients with BRVO-related macular edema to improve their vision
Branch retinal vein occlusion (BRVO) commonly occurs at the arteriovenous crossing in the unilateral eye, and cardiovascular diseases can be risk factors of BRVO. However, the pathomechanism leading to BRVO is...
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Article
Evaluation of granulation tissue formation in lacrimal duct post silicone intubation and its successful management by injection of prednisolone acetate ointment into the lacrimal duct
To evaluate the clinical findings and original treatment method of granulation tissue formation post silicone intubation (SI) for primary acquired lacrimal drainage obstruction (PALDO).
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Article
Optic perineuritis associated with antineutrophil cytoplasmic autoantibody-related hypertrophic pachymeningitis: a case report
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Article
Effect of rebamipide ophthalmic suspension on the success of lacrimal stent intubation
To evaluate the effect of the postoperative administration of rebamipide ophthalmic suspension on the success rate of lacrimal stent intubation (LSI) for the treatment of primary acquired nasolacrimal duct obs...
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Article
Indications for and effects of Nunchaku-style silicone tube intubation for primary acquired lacrimal drainage obstruction
To study the indications for and effectiveness of Nunchaku-style silicone tube intubation (NSTI) in treating primary acquired lacrimal drainage obstruction (PALDO).
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Article
Elderly case of pseudo-unilateral occult macular dystrophy with Arg45Trp mutation in RP1L1 gene
To report a case of pseudo-unilateral occult macular dystrophy (OMD) with an Arg45Trp mutation in the RP1L1 gene and had unilateral functional changes for about 9 years.
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Article
Effects of all-trans retinoic acid nanoparticles on corneal epithelial wound healing
We have developed inorganically-coated all-trans retinoic acid (atRA) nanoparticles, nano-sized egg-like particles of atRA (NANOEGG®-atRA). The purpose of this study was to determine the effects of NANOEGG®-at...
