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Chapter
Regulation of CD36 by PPARγ: Pro- or Antiatherogenic?
The role of PPARγ in the pathogenesis of atherosclerosis has been difficult to predict, and remains an important question because of the widespread use of agonists, such as thiazolidinediones, in humans. Prior...
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Chapter
Uptake of LDL-Sized Particles Extracted from Human Aortic Lesions by Macrophages in Culture
We have isolated a lipoprotein particle, designated A-LDL, from atherosclerotic lesions in human aortas by a combination of affinity chromatography and gel filtration. This lipoprotein, believed to be derived ...
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Chapter and Conference Paper
Low Density Lipoproteins in the Aorta: Relation to Atherosclerosis
A link between plasma low density lipoproteins (LDL) and the atherosclerotic process has been suggested from both clinical-correlative studies in man (Kannel et al. 1964) and diet-fed experimental animal model...
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Article
Ultrastructural localization of plasma lipoproteins in human intracranial arteries
The fine-structural localization of apoB, the major protein constituent of both the low and very low density plasma lipoprotein fractions, was described in human middle cerebral and basilar arteries. Using an ...
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Article
Human intracranial atherosclerosis
Morphology of atheromatous plaques from human intracranial arteries was examined by light and electron microscopy. Overall morphology of lesions did not differ from those reported for other arterial beds. In t...
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Article
Injury to the aortic endothelial lining by vasoactive agents