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Article
Coupled changes between ruminating thoughts and resting-state brain networks during the transition into adulthood
Perseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into adulthood. Due to its multifaceted nature, rumination can take sev...
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Article
Open AccessLight Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing
For decades, cannabis has been the most widely used illicit substance in the world, particularly among youth. Research suggests that mental health problems associated with cannabis use may result from its effe...
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Article
Open AccessIdentifying subgroups with differential response to CBASP versus Escitalopram during the first eight weeks of treatment in outpatients with persistent depressive disorder
There exists little empirical evidence hel** clinicians to select the most effective treatment for individual patients with persistent depressive disorder (PDD). This study identifies and characterizes subgr...
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Article
Open AccessPredictors of adherence to exercise interventions in people with schizophrenia
Exercise interventions are nowadays considered as effective add-on treatments in people with schizophrenia but are usually associated with high dropout rates. Therefore, the present study investigated potentia...
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Article
Open AccessSmaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup
Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when c...
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Article
Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods
Posttraumatic stress disorder (PTSD) is associated with lower cortical thickness (CT) in prefrontal, cingulate, and insular cortices in diverse trauma-affected samples. However, some studies have failed to det...
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Article
Correction: Arc controls alcohol cue relapse by a central amygdala mechanism
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Chapter
Depersonalization Disorder, Emotion Regulation, and Existential Feelings
Depersonalization-derealization disorder (DDD) is a common, though largely neglected, disorder. In this paper, we discuss its phenomenology, epidemiology, and etiology with respect to recent neuroscientific fi...
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Article
Differential associations of adolescent versus young adult cannabis initiation with longitudinal brain change and behavior
Leveraging ~10 years of prospective longitudinal data on 704 participants, we examined the effects of adolescent versus young adult cannabis initiation on MRI-assessed cortical thickness development and behavi...
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Article
Covariation of preadult environmental exposures, adult brain imaging phenotypes, and adult personality traits
Exposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental proce...
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Article
Open AccessHypothalamic volume in pedophilia with or without child sexual offense
The hypothalamus regulates sexual behavior and is simultaneously associated with aggression and violence. Consequently, this brain region is relevant in research of pedophilia and child sexual offenses (CSO). ...
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Article
Open AccessAutistic traits and alcohol use in adolescents within the general population
It has been suggested that autistic traits are associated with less frequent alcohol use in adolescence. Our study seeks to examine the relationship between autistic traits and alcohol use in a large adolescen...
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Article
Open AccessFunctional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies
The promise of machine learning has fueled the hope for develo** diagnostic tools for psychiatry. Initial studies showed high accuracy for the identification of major depressive disorder (MDD) with resting-s...
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Article
Arc controls alcohol cue relapse by a central amygdala mechanism
Alcohol use disorder (AUD) is a chronic and fatal disease. The main impediment of the AUD therapy is a high probability of relapse to alcohol abuse even after prolonged abstinence. The molecular mechanisms of ...
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Article
Open AccessAnxiety onset in adolescents: a machine-learning prediction
Recent longitudinal studies in youth have reported MRI correlates of prospective anxiety symptoms during adolescence, a vulnerable period for the onset of anxiety disorders. However, their predictive value has...
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Article
Cortical profiles of numerous psychiatric disorders and normal development share a common pattern
The neurobiological bases of the association between development and psychopathology remain poorly understood. Here, we identify a shared spatial pattern of cortical thickness (CT) in normative development and...
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Chapter
Determinants of Risk Developmental Trajectories for Risky and Harmful Alcohol Use: Lessons from the IMAGEN Consortium
Adolescence is a key period for the initiation of alcohol drinking. Escalating alcohol use in adolescence, however, increases the risk for develo** alcohol-related problems later in life, including alcohol u...
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Article
Open AccessBehavioural and functional evidence revealing the role of RBFOX1 variation in multiple psychiatric disorders and traits
Common variation in the gene encoding the neuron-specific RNA splicing factor RNA Binding Fox-1 Homolog 1 (RBFOX1) has been identified as a risk factor for several psychiatric conditions, and rare genetic variant...
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Article
A causal association of ANKRD37 with human hippocampal volume
Human hippocampal volume has been separately associated with single nucleotide polymorphisms (SNPs), DNA methylation and gene expression, but their causal relationships remain largely unknown. Here, we aimed a...
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Article
Open AccessOrbitofrontal control of conduct problems? Evidence from healthy adolescents processing negative facial affect
Conduct problems (CP) in patients with disruptive behavior disorders have been linked to impaired prefrontal processing of negative facial affect compared to controls. However, it is unknown whether associatio...