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Article
Coupled changes between ruminating thoughts and resting-state brain networks during the transition into adulthood
Perseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into adulthood. Due to its multifaceted nature, rumination can take sev...
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Article
Open AccessLight Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing
For decades, cannabis has been the most widely used illicit substance in the world, particularly among youth. Research suggests that mental health problems associated with cannabis use may result from its effe...
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Article
Open AccessIdentifying subgroups with differential response to CBASP versus Escitalopram during the first eight weeks of treatment in outpatients with persistent depressive disorder
There exists little empirical evidence hel** clinicians to select the most effective treatment for individual patients with persistent depressive disorder (PDD). This study identifies and characterizes subgr...
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Article
The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders
Despite its crucial role in the regulation of vital metabolic and neurological functions, the genetic architecture of the hypothalamus remains unknown. Here we conducted multivariate genome-wide association st...
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Article
Open AccessPredictors of adherence to exercise interventions in people with schizophrenia
Exercise interventions are nowadays considered as effective add-on treatments in people with schizophrenia but are usually associated with high dropout rates. Therefore, the present study investigated potentia...
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Article
Open AccessSmaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup
Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when c...
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Article
Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods
Posttraumatic stress disorder (PTSD) is associated with lower cortical thickness (CT) in prefrontal, cingulate, and insular cortices in diverse trauma-affected samples. However, some studies have failed to det...
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Article
Correction: Arc controls alcohol cue relapse by a central amygdala mechanism
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Depersonalization Disorder, Emotion Regulation, and Existential Feelings
Depersonalization-derealization disorder (DDD) is a common, though largely neglected, disorder. In this paper, we discuss its phenomenology, epidemiology, and etiology with respect to recent neuroscientific fi...
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Article
Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
The cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here ...
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Article
Open AccessWhole-brain gray matter maturation trajectories associated with autistic traits from adolescence to early adulthood
A growing number of evidence supports a continued distribution of autistic traits in the general population. However, brain maturation trajectories of autistic traits as well as the influence of sex on these t...
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Article
Open AccessMeasuring self-regulation in everyday life: Reliability and validity of smartphone-based experiments in alcohol use disorder
Self-regulation, the ability to guide behavior according to one’s goals, plays an integral role in understanding loss of control over unwanted behaviors, for example in alcohol use disorder (AUD). Yet, experim...
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Article
Differential associations of adolescent versus young adult cannabis initiation with longitudinal brain change and behavior
Leveraging ~10 years of prospective longitudinal data on 704 participants, we examined the effects of adolescent versus young adult cannabis initiation on MRI-assessed cortical thickness development and behavi...
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Article
Covariation of preadult environmental exposures, adult brain imaging phenotypes, and adult personality traits
Exposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental proce...
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Article
Open AccessAuthor Correction: A shared neural basis underlying psychiatric comorbidity
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Article
Open AccessHypothalamic volume in pedophilia with or without child sexual offense
The hypothalamus regulates sexual behavior and is simultaneously associated with aggression and violence. Consequently, this brain region is relevant in research of pedophilia and child sexual offenses (CSO). ...
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Article
Open AccessA stable and replicable neural signature of lifespan adversity in the adult brain
Environmental adversities constitute potent risk factors for psychiatric disorders. Evidence suggests the brain adapts to adversity, possibly in an adversity-type and region-specific manner. However, the long-...
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Article
Open AccessAutistic traits and alcohol use in adolescents within the general population
It has been suggested that autistic traits are associated with less frequent alcohol use in adolescence. Our study seeks to examine the relationship between autistic traits and alcohol use in a large adolescen...
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Article
Open AccessAssociation between vmPFC gray matter volume and smoking initiation in adolescents
Smoking of cigarettes among young adolescents is a pressing public health issue. However, the neural mechanisms underlying smoking initiation and sustenance during adolescence, especially the potential causal ...
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Article
Open AccessFunctional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies
The promise of machine learning has fueled the hope for develo** diagnostic tools for psychiatry. Initial studies showed high accuracy for the identification of major depressive disorder (MDD) with resting-s...
