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  1. No Access

    Article

    Coupled changes between ruminating thoughts and resting-state brain networks during the transition into adulthood

    Perseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into adulthood. Due to its multifaceted nature, rumination can take sev...

    Rocco Marchitelli, Marie-Laure Paillère Martinot, Alain Trouvé in Molecular Psychiatry (2024)

  2. Article

    Open Access

    Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup

    Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when c...

    Ashley A. Huggins, C. Lexi Baird, Melvin Briggs, Sarah Laskowitz in Molecular Psychiatry (2024)

  3. No Access

    Article

    Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods

    Posttraumatic stress disorder (PTSD) is associated with lower cortical thickness (CT) in prefrontal, cingulate, and insular cortices in diverse trauma-affected samples. However, some studies have failed to det...

    ** Yang, Ashley A. Huggins, Delin Sun, C. Lexi Baird in Neuropsychopharmacology (2024)

  4. Article

    Correction: Arc controls alcohol cue relapse by a central amygdala mechanism

    Roberto Pagano, Ahmad Salamian, Janusz Zielinski, Anna Beroun in Molecular Psychiatry (2024)

  5. No Access

    Article

    Differential associations of adolescent versus young adult cannabis initiation with longitudinal brain change and behavior

    Leveraging ~10 years of prospective longitudinal data on 704 participants, we examined the effects of adolescent versus young adult cannabis initiation on MRI-assessed cortical thickness development and behavi...

    Matthew D. Albaugh, Max M. Owens, Anthony Juliano in Molecular Psychiatry (2023)

  6. No Access

    Article

    Covariation of preadult environmental exposures, adult brain imaging phenotypes, and adult personality traits

    Exposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental proce...

    Kaizhong Xue, Bo Gao, Feng Chen, Meiyun Wang, **gliang Cheng in Molecular Psychiatry (2023)

  7. Article

    Open Access

    Functional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies

    The promise of machine learning has fueled the hope for develo** diagnostic tools for psychiatry. Initial studies showed high accuracy for the identification of major depressive disorder (MDD) with resting-s...

    Selene Gallo, Ahmed El-Gazzar, Paul Zhutovsky, Rajat M. Thomas in Molecular Psychiatry (2023)

  8. No Access

    Article

    Arc controls alcohol cue relapse by a central amygdala mechanism

    Alcohol use disorder (AUD) is a chronic and fatal disease. The main impediment of the AUD therapy is a high probability of relapse to alcohol abuse even after prolonged abstinence. The molecular mechanisms of ...

    Roberto Pagano, Ahmad Salamian, Janusz Zielinski, Anna Beroun in Molecular Psychiatry (2023)

  9. Article

    Open Access

    Anxiety onset in adolescents: a machine-learning prediction

    Recent longitudinal studies in youth have reported MRI correlates of prospective anxiety symptoms during adolescence, a vulnerable period for the onset of anxiety disorders. However, their predictive value has...

    Alice V. Chavanne, Marie Laure Paillère Martinot, Jani Penttilä in Molecular Psychiatry (2023)

  10. No Access

    Article

    Cortical profiles of numerous psychiatric disorders and normal development share a common pattern

    The neurobiological bases of the association between development and psychopathology remain poorly understood. Here, we identify a shared spatial pattern of cortical thickness (CT) in normative development and...

    Zhipeng Cao, Renata B. Cupertino, Jonatan Ottino-Gonzalez in Molecular Psychiatry (2023)

  11. Article

    Open Access

    Behavioural and functional evidence revealing the role of RBFOX1 variation in multiple psychiatric disorders and traits

    Common variation in the gene encoding the neuron-specific RNA splicing factor RNA Binding Fox-1 Homolog 1 (RBFOX1) has been identified as a risk factor for several psychiatric conditions, and rare genetic variant...

    Aet O’Leary, Noèlia Fernàndez-Castillo, Gabriela Gan, Yunbo Yang in Molecular Psychiatry (2022)

  12. No Access

    Article

    A causal association of ANKRD37 with human hippocampal volume

    Human hippocampal volume has been separately associated with single nucleotide polymorphisms (SNPs), DNA methylation and gene expression, but their causal relationships remain largely unknown. Here, we aimed a...

    Jiayuan Xu, **anyou **a, Qiaojun Li, Yan Dou, **njun Suo, Zuhao Sun in Molecular Psychiatry (2022)

  13. Article

    Open Access

    Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning

    While there is substantial evidence that cannabis use is associated with differences in human brain development, most of this evidence is correlational in nature. Bayesian causal network (BCN) modeling attempt...

    Max M. Owens, Matthew D. Albaugh, Nicholas Allgaier in Translational Psychiatry (2022)

  14. Article

    Open Access

    Intact neural and behavioral correlates of emotion processing and regulation in weight-recovered anorexia nervosa: a combined fMRI and EMA study

    Altered emotion processing and regulation mechanisms play a key role in eating disorders. We recently reported increased fMRI responses in brain regions involved in emotion processing (amygdala, dorsolateral p...

    Maria Seidel, Sophie Pauligk, Sophia Fürtjes, Joseph A. King in Translational Psychiatry (2022)

  15. Article

    Open Access

    Correction: Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders

    Nils Opel, Anbupalam Thalamuthu, Yuri Milaneschi, Dominik Grotegerd in Molecular Psychiatry (2021)

  16. Article

    Open Access

    Altered resting-state functional connectome in major depressive disorder: a mega-analysis from the PsyMRI consortium

    Major depressive disorder (MDD) is associated with abnormal neural circuitry. It can be measured by assessing functional connectivity (FC) at resting-state functional MRI, that may help identifying neural mark...

    Nooshin Javaheripour, Meng Li, Tara Chand, Axel Krug in Translational Psychiatry (2021)

  17. No Access

    Article

    Examination of the association between exposure to childhood maltreatment and brain structure in young adults: a machine learning analysis

    Exposure to maltreatment during childhood is associated with structural changes throughout the brain. However, the structural differences that are most strongly associated with maltreatment remain unclear give...

    Matthew Price, Matthew Albaugh, Sage Hahn, Anthony C. Juliano in Neuropsychopharmacology (2021)

  18. Article

    Open Access

    Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group

    Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced brain aging in adult MDD patients, and whether this ...

    Laura K. M. Han, Richard Dinga, Tim Hahn, Christopher R. K. Ching in Molecular Psychiatry (2021)

  19. Article

    Open Access

    Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders

    Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed to clarify the relationship between obesity and brain structure using structural MRI (n = 6420) and genetic data ...

    Nils Opel, Anbupalam Thalamuthu, Yuri Milaneschi, Dominik Grotegerd in Molecular Psychiatry (2021)

  20. Article

    Open Access

    Linked patterns of biological and environmental covariation with brain structure in adolescence: a population-based longitudinal study

    Adolescence is a period of major brain reorganization shaped by biologically timed and by environmental factors. We sought to discover linked patterns of covariation between brain structural development and a ...

    Amirhossein Modabbernia, Abraham Reichenberg, Alex Ing in Molecular Psychiatry (2021)

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