-
Article
Open AccessLight Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing
For decades, cannabis has been the most widely used illicit substance in the world, particularly among youth. Research suggests that mental health problems associated with cannabis use may result from its effe...
-
Article
Open AccessThe dissociative subtype of posttraumatic stress disorder is associated with subcortical white matter network alterations
Posttraumatic stress disorder (PTSD) is characterized by intrusions, avoidance, and hyperarousal while patients of the dissociative subtype (PTSD-D) experience additional dissociative symptoms. A neurobiologic...
-
Article
Longitudinal associations between amygdala reactivity and cannabis use in a large sample of adolescents
The amygdala is a key brain structure to study in relation to cannabis use as reflected by its high-density of cannabinoid receptors and functional reactivity to processes relevant to drug use. Previously, we ...
-
Article
Open AccessHuman subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors i...
-
Article
Open AccessThe ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutio...
-
Article
Automatic approach bias towards smoking cues is present in smokers but not in ex-smokers
Drug-addicted individuals show automatic approach tendencies towards drug-related cues, i.e., an approach bias (ApB). Nevertheless, little is known about ApB in tobacco smokers and about the presence of ApB af...
-
Article
Nicotine differentially modulates antisaccade performance in healthy male non-smoking volunteers stratified for low and high accuracy
Nicotinergic agents are currently examined as possible pro-cognitive drugs for a variety of clinical conditions marked by cognitive deficits, such as attention deficit hyperactivity disorder (ADHD) or schizoph...
-
Article
Altered reward functions in patients on atypical antipsychotic medication in line with the revised dopamine hypothesis of schizophrenia
To study the mesolimbic dopamine system during expectation and receipt or omission of rewards in partially remitted patients with schizophrenia treated with the atypical antipsychotic olanzapine.
-
Article
Human reward system activation is modulated by a single dose of olanzapine in healthy subjects in an event-related, double-blind, placebo-controlled fMRI study
Olanzapine is a neuroleptic drug widely prescribed to treat schizophrenia and bipolar disorder. Although it is long known that modulation of the dopamine system is a basic mechanism of action of neuroleptics, ...
-
Article
Side Effects of Transcranial Magnetic Stimulation Biased Task Performance in a Cognitive Neuroscience Study
Transcranial magnetic stimulation (TMS) is increasingly used as a research tool for functional brain map** in cognitive neuroscience. Despite being mostly tolerable, side effects of TMS could influence task ...
-
Article
Individual somatotopy of primary sensorimotor cortex revealed by intermodal matching of MEG, PET, and MRI
A method for comparing estimated magnetoencephalographic (MEG) dipole localizations with regional cerebral blood flow (rCBF) activation areas is presented. This approach utilizes individual intermodal matching...