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  1. No Access

    Article

    Quercetin suppresses pancreatic ductal adenocarcinoma progression via inhibition of SHH and TGF-β/Smad signaling pathways

    Pancreatic ductal adenocarcinoma (PDA) is an aggressive type of malignant tumor with a poor prognosis and high mortality. Aberrant activation of hedgehog signaling plays a crucial role in the maintenance and p...

    Yangyang Guo, Yu Tong, Hengyue Zhu, Yanyi **ao… in Cell Biology and Toxicology (2021)

  2. Article

    Open Access

    The anthelmintic drug niclosamide induces GSK-β-mediated β-catenin degradation to potentiate gemcitabine activity, reduce immune evasion ability and suppress pancreatic cancer progression

    Niclosamide, a cell-permeable salicylanilide, was approved by the Food and Drug Administration for its anthelmintic efficiency. A growing body of evidence in recent years suggests that niclosamide exhibits pot...

    Yangyang Guo, Hengyue Zhu, Yanyi **ao, Hangcheng Guo, Miaomiao Lin… in Cell Death & Disease (2022)

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  3. Article

    Open Access

    Correction: The anthelmintic drug niclosamide induces GSK-β-mediated β-catenin degradation to potentiate gemcitabine activity, reduce immune evasion ability and suppress pancreatic cancer progression

    Yangyang Guo, Hengyue Zhu, Yanyi **ao, Hangcheng Guo, Miaomiao Lin… in Cell Death & Disease (2022)

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