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Short-arm human centrifugation with 0.4g at eye and 0.75g at heart level provides similar cerebrovascular and cardiovascular responses to standing
Orthostatic intolerance continues to be a problem with astronauts upon return to Earth as a result of cerebral and cardiovascular adaptations to weightlessness. We tested the hypothesis that artificial gravity...
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Article
Modulation of plasma adrenomedullin by epinephrine infusion during head up tilt
We investigated whether head up tilt (HUT) with and without simultaneous epinephrine infusion modulate plasma adrenomedullin. We studied eight healthy male volunteers, using two 5 min 70° HUT trials: control (...
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Article
Gravity, the hydrostatic indifference concept and the cardiovascular system
Gravity, like any acceleration, causes a hydrostatic pressure gradient in fluid-filled bodily compartments. At a force of 1G, this pressure gradient amounts to 10 kPa/m. Postural changes alter the distribution...
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Intermittent hypoxic training: risks versus benefits
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Patterns of Cardiovascular Control During Repeated Tests of Orthostatic Loading
To investigate patterns of cardiovascular control, a protocol of head up tilt (HUT) followed by lower body negative pressure (LBNP), which represents a significant cardiovascular control challenge, was employe...
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Article
Adrenomedullin and elements of orthostatic competence after 41 h of voluntary submersion in water as measured in four healthy males
Four men established a new score (Guinness Book of Records) by staying submersed in thermoneutral water (average diving depth 2.5 m) for 41 h without slee**. The aim of this study is to measure circulating horm...
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Article
The continuous high-precision measurement of the density of flowing blood
The “mechanical oscillator” technique for the measurement of the density of fluids is based on the influence of mass on the natural frequency of a mechanical oscillator. The practical application of this princ...
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Article
Spectral analysis of spontaneous contractions of the isolated portal vein of rats
The spontaneous contractions of segments of rat portal veins have been examined in vitro under isotonic and isometric conditions. The power density spectra of recorded time series lasting 10–60 min were calcul...