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Article
Open AccessSentinel lymph node biopsy for high-thickness cutaneous squamous cell carcinoma
Squamous cell carcinomas are among the most common skin tumors and show a risk of metastasis depending on various factors such as tumor thickness, localization, histological subtype and immune status of the pa...
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Article
Open AccessChirurgische Techniken in der Therapie des Basalzellkarzinoms – eine prospektive Untersuchung
Basalzellkarzinome sind die häufigsten epithelialen Hauttumoren und eine häufige Indikation für dermatologische Eingriffe. Trotz der Etablierung medikamentöser Therapieoptionen stellt die Operation weiterhin d...
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Article
Lymph node dissection for melanoma using tumescence local anaesthesia: an observational study
The possibility that tumescence local anaesthesia (TLA) may lead to dissemination of tumour cells in lymph nodes is presently unclear.
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Article
Surgical treatment of rhinophyma: experience from a German cohort of 70 patients
Rhinophyma is a deforming soft tissue hyperplasia of the nose and surgical removal represents the treatment of choice. Comprehensive data on surgical therapy and the impact of rhinophyma on patient quality of ...
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Article
Cytokeratin AE1/AE3 immunostaining and 3D-histology: improvement of diagnosis in desmoplastic squamous cell carcinoma of the skin
Desmoplastic squamous cell carcinoma (DSCC) as a rare subtype of cutaneous SCC has specific histological features, characterized by columns, bands, and strands of squamoid cells infiltrating a dense collagenou...
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Book
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Chapter
Terminology and Facts
Mohs termed the excision of tumor tissues with the aid of a histological evaluation “microscopically controlled surgery” (MCS), and in its original meaning it is different from the “vertical serial cutting” (l...
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Chapter
The Basics for Excision and Flattening
In this chapter, the basic principles of tumor excisions will be discussed. By introducing several different methods for tumor excisions and converting 3D margins to a 2D plane, the reader will be given the op...
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Chapter
Dividing Tumors and Topographical Orientation
So far only on examples of small tumors in which the excised tumor specimen fitted completely in the device for histological sectioning were discussed. If tumors are larger due to their advanced growth or larg...
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Chapter
The Aftermath or How to Excise Until Clear Margins
As we have seen in the previous chapter, topographic landmarks facilitate the precise localization of tumor-positive outgrowths in the entire 3D margins. With the help of this information, the surgeon can then...
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Chapter
How to Perform 3D Histology on Different Types of Tumors
3D histology is intended for tumors at difficult sites where a tissue-saving surgical technique is needed or if local R0 resection must be ensured due to the aggressive growth of the tumor (Table 8.1) [1]. Pre...
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Chapter
Introduction
In the past, a lot of individual surgery procedures and histopathological investigation for skin tumors have been extensively discussed in the literature, e.g., Mohs’ surgery and methods of other disciplines a...
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Chapter
Embedding and Sectioning
Following the excision of the tumor tissue and the conversion of the 3D tumor margins into a 2D plane, the tissue samples will have to be embedded and sectioned. There are two alternative commonly used techniq...
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Chapter
Communication with the Lab
The management of a full 3D histology needs a tight communication between the surgeon and the pathologist. Clear and safe rules are necessary to enable both the surgeon and the pathologist to point out areas o...
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Chapter
Variations for Special Locations and Large, Deep Penetrating Tumors
In this chapter, the excision of tumors growing at special locations such as nose, lips, eyelid, and ear will be discussed. The natural border of the anatomy of these tissues restrains the possibilities for tu...
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Article
Seventh Edition American Joint Committee on Cancer Staging of Cutaneous Non-Melanoma Skin Cancer
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Chapter
Chirurgie des Melanoms in akraler und fazialer Lokalisation mit 3D-Histologie (mikrographische/histographische Chirurgie)
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Article
Interdisziplinäre Leitlinie: Acne inversa (Entwicklungsstufe S1)
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Article
Acne inversa – Interdisziplinäre Leitlinien der Deutschen Dermatologischen Gesellschaft – Berufsverband der Deutschen Dermatologen e. V., Subkommission Proktologie
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Chapter and Conference Paper
Subkutane Infusionsanästhesie (SIA), eine schmerzarme, halbautomatische Tumeszenzlokalanästhesie
Tumescere bedeutet anschwellen, bedingt durch die Infiltration großer Mengen verdünnter Lokalanästhetika. Schon der deutsche Chirurg Schleich hatte 1892 auf die Tatsache hingewiesen [14], dass au...
