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  1. Article

    Open Access

    Efficient self-assembly and protective efficacy of infectious bursal disease virus-like particles by a recombinant baculovirus co-expressing precursor polyprotein and VP4

    Virus-like particle (VLP) technology is considered one of the most promising approaches in animal vaccines, due to the intrinsic immunogenic properties as well as high safety profile of VLPs. In this study, we...

    Hyun-Jeong Lee, Ji-Ye Kim, Soo-jeong Kye, Hee-Jung Seul, Suk-Chan Jung in Virology Journal (2015)

  2. No Access

    Article

    Over-expression of a RhoA-specific guanine nucleotide exchange factor, p190RhoGEF, in mouse dendritic cells negatively regulates cellular responses to bacterial lipopolysaccharide

    We studied the role of a RhoA-specific guanine nucleotide exchange factor (p190RhoGEF) in dendritic cells (DCs), using transgenic (TG) mice that over-express a full gene of p190RhoGEF under the control of an i...

    Hee Jung Seul, Yu Ri Ahn, Hyeon Myeong Song, Yun Jung Ha in Molecules and Cells (2012)

  3. Article

    Open Access

    Ligation of CD40 receptor in human B lymphocytes triggers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK

    Previously, we reported that CD40-induced production of reactive oxygen species (ROS) by NADPH oxidase requires the TNF receptor-associated factor (TRAF) 3, as well as the activities of phosphatidylinositol 3-...

    Yun Jung Ha, Hee Jung Seul, Jong Ran Lee in Experimental & Molecular Medicine (2011)