-
Chapter
Discoidin Domain Receptors in Invertebrates
Discoidin domain receptors (DDRs) are evolutionary conserved and found in the genomes of all but the simplest metazoans. DDRs have neither been completely lost in larger animal phyla nor expanded beyond a smal...
-
Article
Open AccessA survey of putative secreted and transmembrane proteins encoded in the C. elegans genome
Almost half of the Caenorhabditis elegans genome encodes proteins with either a signal peptide or a transmembrane domain. Therefore a substantial fraction of the proteins are localized to membranes, reside in the...
-
Article
Open AccessCharacterization of the astacin family of metalloproteases in C. elegans
Astacins are a large family of zinc metalloproteases found in bacteria and animals. They have diverse roles ranging from digestion of food to processing of extracellular matrix components. The C. elegans genome c...
-
Article
Open AccessGExplore: a web server for integrated queries of protein domains, gene expression and mutant phenotypes
The majority of the genes even in well-studied multi-cellular model organisms have not been functionally characterized yet. Mining the numerous genome wide data sets related to protein function to retrieve pot...
-
Article
Open AccessIgCAMs redundantly control axon navigation in Caenorhabditis elegans
Cell adhesion molecules of the immunoglobulin superfamily (IgCAMs) form one of the largest and most diverse families of adhesion molecules and receptors in the nervous system. Many members of this family media...
-
Protocol
Fluorescent Reporter Methods
The identification and cloning of the green fluorescent protein (GFP) from jellyfish marks the beginning of a new era of fluorescent reporters. In Caenorhabditis elegans, genetically encoded markers like the fluo...
