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  1. Article

    Open Access

    Antitumor efficacy and potential mechanism of FAP-targeted radioligand therapy combined with immune checkpoint blockade

    Radiotherapy combined with immune checkpoint blockade holds great promise for synergistic antitumor efficacy. Targeted radionuclide therapy delivers radiation directly to tumor sites. LNC1004 is a fibroblast a...

    Liang Zhao, Yizhen Pang, Yangfan Zhou in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    Assessing peptic ulcer risk with the HAMPROW score in the general Chinese population

    The timely identification of individuals at high risk for peptic ulcers (PUs) is vital in preventing gastrointestinal bleeding after antiplatelet therapy. This study was designed to determine PU risk factors a...

    Binli Wang, Weitao Yu, Zheyu Zhang, Weili **, Haojun Chen in Scientific Reports (2024)

  3. No Access

    Article

    A phase 1 trial to determine the maximum tolerated dose and patient-specific dosimetry of [177Lu]Lu-LNC1003 in patients with metastatic castration-resistant prostate cancer

    This translational study aimed to determine the maximum tolerated dose (MTD), safety, dosimetry, and therapeutic efficacy of 177Lu-PSMA-EB-01 (denoted as [177Lu]Lu-LNC1003) in patients with metastatic castration-...

    Jie Zang, Guochang Wang, Tianzhi Zhao in European Journal of Nuclear Medicine and M… (2024)

  4. No Access

    Article

    SSTR antagonist [68Ga]Ga-DOTA-LM3 differentiates intrapancreatic accessory spleen from neuroendocrine tumor in a patient presenting indeterminate MRI and SSTR agonist [68Ga]Ga-DOTATATE

    Weizhi Xu, Jiayu Cai, Tinghua Meng in European Journal of Nuclear Medicine and M… (2024)

  5. No Access

    Article

    FAP expression in alpha cells of Langherhans insulae—implications for FAPI radiopharmaceuticals’ use

    Radiopharmaceuticals targeting fibroblast activation protein (FAP) alpha are increasingly studied for diagnostic and therapeutic applications. We discovered FAP expression at immunohistochemistry (IHC) in the ...

    Margarita Kirienko, Giovanni Centonze in European Journal of Nuclear Medicine and M… (2023)

  6. No Access

    Article

    Extranodal Rosai-Dorfman disease involving pulmonary artery detected by 68Ga-FAPI PET/CT and fused 68Ga-FAPI PET/MRI

    Liang Zhao, Yizhen Pang, Long Sun, Qin Lin in European Journal of Nuclear Medicine and M… (2023)

  7. No Access

    Article

    Identification of isolated hepatic sarcoidosis with [18F]FDG and [68 Ga]Ga-FAPI PET/CT

    Yizhen Pang, Peipei Wang, Weizhi Xu in European Journal of Nuclear Medicine and M… (2023)

  8. No Access

    Article

    [68 Ga]Ga-DOTATATE PET/CT versus [68 Ga]Ga-Exendin-4 PET/CT in the evaluation of metastatic insulinoma

    Wei Guo, Yuhang Chen, **aojiang He, Hao Fu in European Journal of Nuclear Medicine and M… (2023)

  9. No Access

    Article

    Comparison of [68Ga]Ga-FAPI and [18F]FDG uptake in patients with gastric signet-ring-cell carcinoma: a multicenter retrospective study

    In this study, we investigated the role of [68Ga]Ga-FAPI PET imaging in the detection of primary and metastatic gastric signet-ring-cell carcinoma (GSRCC) and compared with [18F]FDG PET.

    Haojun Chen, Yizhen Pang, Junpeng Li, Fei Kang, Weizhi Xu in European Radiology (2023)

  10. No Access

    Article

    Prognostic value of fibroblast activation protein expressing tumor volume calculated from [68 Ga]Ga-FAPI PET/CT in patients with esophageal squamous cell carcinoma

    This study aimed to investigate the prognostic value of semiquantitative parameters derived from [68 Ga]Ga-fibroblast activation protein inhibitor (FAPI) PET/CT for patients with esophageal squamous cell carcinom...

    Liang Zhao, Yizhen Pang, Shanyu Chen in European Journal of Nuclear Medicine and M… (2023)

  11. No Access

    Article

    68Ga-FAPI PET/CT detected non-FDG-avid bone metastases in breast cancer

    Qihang Shang, Bing Hao, Weizhi Xu in European Journal of Nuclear Medicine and M… (2022)

  12. No Access

    Article

    [68Ga]Ga-FAPI PET/CT imaging of brown tumors in a patient with primary hyperparathyroidism

    Yizhen Pang, Qihang Shang, Tinghua Meng in European Journal of Nuclear Medicine and M… (2022)

  13. No Access

    Article

    FAP-targeted radionuclide therapy with [177Lu]Lu-FAPI-46 in metastatic nasopharyngeal carcinoma

    Kaili Fu, Yizhen Pang, Liang Zhao, Limei Lin in European Journal of Nuclear Medicine and M… (2022)

  14. No Access

    Article

    Positron emission tomography and computed tomography with [68Ga]Ga-fibroblast activation protein inhibitors improves tumor detection and staging in patients with pancreatic cancer

    This study aimed to investigate the diagnostic performance of [68Ga]Ga-FAPI PET/CT for primary and metastatic pancreatic carcinoma lesions and compare the results with those of [18F]-fluorodeoxyglucose ([18F]FDG)...

    Yizhen Pang, Long Zhao, Qihang Shang in European Journal of Nuclear Medicine and M… (2022)

  15. No Access

    Article

    Somatostatin receptor imaging with [68Ga]Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) in patients with nasopharyngeal carcinoma

    To explore the feasibility of [68Ga]Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) in patients with non-keratinizing nasopharyngeal carcinoma (NPC) and to evaluate whether [68Ga]Ga-DOTATATE...

    Liang Zhao, Yizhen Pang, Yuhuan Wang in European Journal of Nuclear Medicine and M… (2022)

  16. No Access

    Article

    Increased [68 Ga]Ga-FAPI uptake in focal nodular hyperplasia in a patient with sigmoid colon cancer

    Qihang Shang, Li Fu, Yizhen Pang in European Journal of Nuclear Medicine and M… (2021)

  17. No Access

    Article

    Clinical utility of [68Ga]Ga-labeled fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography for primary staging and recurrence detection in nasopharyngeal carcinoma

    This study aimed to explore the clinical utility of [68Ga]Ga-labeled fibroblast activation protein inhibitor ([68Ga]Ga-FAPI) positron emission tomography/computed tomography (PET/CT) relative to [18F]-fluorodeoxy...

    Liang Zhao, Yizhen Pang, Hua Zheng in European Journal of Nuclear Medicine and M… (2021)

  18. No Access

    Article

    Role of [68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of peritoneal carcinomatosis and comparison with [18F]-FDG PET/CT

    The aim of this study was to explore the role of [68Ga]Ga-DOTA-FAPI-04 positron emission tomography/computed tomography (PET/CT), compared with 18F-fluorodeoxyglucose [18F]-FDG PET/CT, for evaluating peritoneal c...

    Liang Zhao, Yizhen Pang, Zuoming Luo in European Journal of Nuclear Medicine and M… (2021)

  19. No Access

    Article

    Imaging fibroblast activation protein in liver cancer: a single-center post hoc retrospective analysis to compare [68Ga]Ga-FAPI-04 PET/CT versus MRI and [18F]-FDG PET/CT

    This study aimed to evaluate the potential utility of [68Ga]Ga-FAPI-04 PET/CT for diagnosing primary and metastatic lesions in patients with liver cancer, as well as to compare it with contrast-enhanced CT (CE-CT...

    Wei Guo, Yizhen Pang, Lanlin Yao, Liang Zhao in European Journal of Nuclear Medicine and M… (2021)

  20. No Access

    Article

    [18F]FDG and [68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of tuberculous lesions

    Bing Hao, **urong Wu, Yizhen Pang, Long Sun in European Journal of Nuclear Medicine and M… (2021)

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