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  1. No Access

    Article

    Sagittal en bloc resection of thoracolumbar tumours: a report of thirty one cases

    To develop a novel classification of sagittal en bloc resection (SEBR) based on anatomical locations for thoracolumbar spine tumors and assess the clinical outcomes of this surgical procedure.

    **aojun Zhu, **xin Hu, Wenquan Xu, Guohui Song, Huaiyuan Xu in International Orthopaedics (2024)

  2. Article

    Open Access

    Different humidity environments do not affect the subsequent exercise ability of college football players after aerobic high-intensity interval training

    Previous studies have explored the effect of differing heat and relative humidity (RH) environments on the performance of multiple anaerobic high-intensity interval training (HIIT). Still, its impact on physio...

    Yongzhao Fan, Ben Zhang, Yan Wang, Hao Wu in Scientific Reports (2024)

  3. Article

    Open Access

    YTH domain family protein 3 accelerates non-small cell lung cancer immune evasion through targeting CD8+ T lymphocytes

    Immune evasion is one of the critical hallmarks of malignant tumors, especially non-small cell lung cancer (NSCLC). Emerging findings have illustrated the roles of N6-methyladenosine (m6A) on NSCLC immune evasion...

    Yisheng Luo, Chao Zeng, Zezhong Ouyang, Wenbin Zhu, Jiazhi Wang in Cell Death Discovery (2024)

  4. Article

    Open Access

    Knockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer

    This study aims to reveal the relationship between AMIGO2 and proliferation, migration and tumorigenicity of bladder cancer, and explore the potential molecular mechanisms.

    Dali Han, Bin **ong, **angxiang Zhang, Chaohu Chen, Zhiqiang Yao, Hao Wu in Hereditas (2024)

  5. Article

    Open Access

    Localized fine-tuning and clinical evaluation of deep-learning based auto-segmentation (DLAS) model for clinical target volume (CTV) and organs-at-risk (OAR) in rectal cancer radiotherapy

    Various deep learning auto-segmentation (DLAS) models have been proposed, some of which have been commercialized. However, the issue of performance degradation is notable when pretrained models are deployed in...

    Jianhao Geng, **n Sui, Rongxu Du, Jialin Feng, Ruoxi Wang in Radiation Oncology (2024)

  6. Article

    Open Access

    Correction: Facile synthesis of amino-modified magnetic covalent organic framework for the efficient extraction and determination of anionic azo dyes in carbonated beverages

    Shu** Guan, Hao Wu, Wanming Lin, Yaxin Chen, Zhuliang Wang in Analytical Sciences (2024)

  7. No Access

    Article

    Facile synthesis of amino-modified magnetic covalent organic framework for the efficient extraction and determination of anionic azo dyes in carbonated beverages

    In this work, a novel magnetic covalent organic framework (COF (TpPa-NH2) @ Fe3O4) was prepared via two step by simple solvent method for the extraction of anionic azo dye residues in food. The as-prepared COF (T...

    Shu** Guan, Hao Wu, Wanming Lin, Yaxin Chen, Zhuliang Wang in Analytical Sciences (2024)

  8. No Access

    Article

    On a Navier–Stokes–Cahn–Hilliard system for viscous incompressible two-phase flows with chemotaxis, active transport and reaction

    We analyze a Navier–Stokes–Cahn–Hilliard model for viscous incompressible two-phase flows where the mechanisms of chemotaxis, active transport and reaction are taken into account. The evolution system couples ...

    **gning He, Hao Wu in Mathematische Annalen (2024)

  9. No Access

    Article

    Enhancing osteogenic bioactivities of coaxial electrospinning nano-scaffolds through incorporating iron oxide nanoparticles and icaritin for bone regeneration

    Bone tissue engineering provides a promising strategy for the treatment of bone defects. Nonetheless, the clinical utilization of biomaterial-based scaffolds is constrained by their inadequate mechanical stren...

    Peng Wang, Qian** Wang, Dengxian Wu, Yunyang Zhang, Shixiong Kang in Nano Research (2024)

  10. No Access

    Article

    Mechanistic insights from inflammasome structures

    Inflammasomes are supramolecular complexes that form in the cytosol in response to pathogen-associated and damage-associated stimuli, as well as other danger signals that perturb cellular homoeostasis, resulti...

    Jianing Fu, Kate Schroder, Hao Wu in Nature Reviews Immunology (2024)

  11. Article

    Open Access

    Alterations of the bile microbiome is associated with progression-free survival in pancreatic ductal adenocarcinoma patients

    Patients with pancreatic ductal adenocarcinoma (PDAC) display an altered oral, gastrointestinal, and intra-pancreatic microbiome compared to healthy individuals. However, knowledge regarding the bile microbiom...

    Hang Jiang, Yitong Tian, Linwei Xu, **ng Chen, Yurun Huang, Jia Wu in BMC Microbiology (2024)

  12. Article

    Open Access

    Slit2–Robo4 signal pathway and tight junction in intestine mediate LPS-induced inflammation in mice

    Sepsis is one of the most common clinical diseases, which is characterized by a serious and uncontrollable inflammatory response. LPS-induced inflammation is a critical pathological event in sepsis, but the un...

    Lv Wang, Yingtai Chen, Hao Wu, He-hua Yu, Linhao Ma in European Journal of Medical Research (2024)

  13. Article

    Open Access

    Rapid improvement of grain appearance in three-line hybrid rice via CRISPR/Cas9 editing of grain size genes

    Genetic editing of grain size genes quickly improves three-line hybrid rice parents to increase the appearance quality and yield of hybrid rice.

    Juan Huang, Weiwei Chen, Lijun Gao, Dong** Qing in Theoretical and Applied Genetics (2024)

  14. No Access

    Article

    Electron Microscopic Map** of Mitochondrial Morphology in the Cochlear Nerve Fibers

    To enable nervous system function, neurons are powered in a use-dependent manner by mitochondria undergoing morphological-functional adaptation. In a well-studied model system—the mammalian cochlea, auditory n...

    Yan Lu, Yi Jiang, Fangfang Wang, Hao Wu in Journal of the Association for Research in… (2024)

  15. No Access

    Article

    The value of ictal scalp EEG in focal epilepsies surgery: a retrospective analysis

    To describe the association between preoperative ictal scalp electroencephalogram (EEG) results and surgical outcomes in patients with focal epilepsies.

    Huanfa Li, Qiang Meng, Yong Liu, Hao Wu, Yicong Dong, Yutao Ren in Neurological Sciences (2024)

  16. Article

    Open Access

    Plasma circulating tumor DNA unveils the efficacy of PD-1 inhibitors and chemotherapy in advanced gastric cancer

    Programmed Death Receptor 1 (PD-1) inhibitors, when combined with chemotherapy, have exhibited notable effectiveness in enhancing the survival outcomes of patients afflicted with advanced gastric cancer. Howev...

    Rongqi Jiang, Xu Cheng, ** Li, Enqing Meng, **nyi Wu, Hao Wu in Scientific Reports (2024)

  17. Article

    Open Access

    Landform and lithospheric development contribute to the assembly of mountain floras in China

    Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...

    Wan-Yi Zhao, Zhong-Cheng Liu, Shi Shi, Jie-Lan Li, Ke-Wang Xu in Nature Communications (2024)

  18. Article

    Open Access

    Real-world performance of HIV low viral load values in diagnosing acute HIV infection in a tertiary care hospital in Bei**g, China

    Early diagnosis of HIV infection decreases the time from HIV diagnosis to viral suppression and reduces further HIV transmission. The Chinese Guidelines for the Diagnosis and Treatment of HIV/AIDS (2021 editio...

    Li Li, **a Feng, Fei Zhao, Defu Yuan, **zhao An, **aoxue Tian in BMC Infectious Diseases (2024)

  19. Article

    Open Access

    Metabolic syndrome parameters' variability and stroke incidence in hypertensive patients: evidence from a functional community cohort

    Stroke is a common complication of hypertension, but the predictive value of metabolic syndrome parameters' variability on stroke risk in individuals with hypertension remains unclear. Therefore, our objective...

    Qitong Liu, Shouling Wu, **ang Shao, Yang Liu, Yanqiu Lu in Cardiovascular Diabetology (2024)

  20. Article

    Open Access

    Genetic Effects of Grain Quality Enhancement in Indica Hybrid Rice: Insights for Molecular Design Breeding

    Improving rice quality remains a crucial breeding objective, second only to enhancing yield, yet progress in quality improvement lags behind yield. The high temperature and ripening conditions in Southern Chin...

    Ju Gao, Lijun Gao, Weiwei Chen, Juan Huang, Dong** Qing, Yinghua Pan, Chonglie Ma in Rice (2024)

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