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1,719 Result(s)
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Article
Sagittal en bloc resection of thoracolumbar tumours: a report of thirty one cases
To develop a novel classification of sagittal en bloc resection (SEBR) based on anatomical locations for thoracolumbar spine tumors and assess the clinical outcomes of this surgical procedure.
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Open AccessDifferent humidity environments do not affect the subsequent exercise ability of college football players after aerobic high-intensity interval training
Previous studies have explored the effect of differing heat and relative humidity (RH) environments on the performance of multiple anaerobic high-intensity interval training (HIIT). Still, its impact on physio...
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Open AccessYTH domain family protein 3 accelerates non-small cell lung cancer immune evasion through targeting CD8+ T lymphocytes
Immune evasion is one of the critical hallmarks of malignant tumors, especially non-small cell lung cancer (NSCLC). Emerging findings have illustrated the roles of N6-methyladenosine (m6A) on NSCLC immune evasion...
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Open AccessKnockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer
This study aims to reveal the relationship between AMIGO2 and proliferation, migration and tumorigenicity of bladder cancer, and explore the potential molecular mechanisms.
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Open AccessLocalized fine-tuning and clinical evaluation of deep-learning based auto-segmentation (DLAS) model for clinical target volume (CTV) and organs-at-risk (OAR) in rectal cancer radiotherapy
Various deep learning auto-segmentation (DLAS) models have been proposed, some of which have been commercialized. However, the issue of performance degradation is notable when pretrained models are deployed in...
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Open AccessCorrection: Facile synthesis of amino-modified magnetic covalent organic framework for the efficient extraction and determination of anionic azo dyes in carbonated beverages
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Facile synthesis of amino-modified magnetic covalent organic framework for the efficient extraction and determination of anionic azo dyes in carbonated beverages
In this work, a novel magnetic covalent organic framework (COF (TpPa-NH2) @ Fe3O4) was prepared via two step by simple solvent method for the extraction of anionic azo dye residues in food. The as-prepared COF (T...
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On a Navier–Stokes–Cahn–Hilliard system for viscous incompressible two-phase flows with chemotaxis, active transport and reaction
We analyze a Navier–Stokes–Cahn–Hilliard model for viscous incompressible two-phase flows where the mechanisms of chemotaxis, active transport and reaction are taken into account. The evolution system couples ...
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Enhancing osteogenic bioactivities of coaxial electrospinning nano-scaffolds through incorporating iron oxide nanoparticles and icaritin for bone regeneration
Bone tissue engineering provides a promising strategy for the treatment of bone defects. Nonetheless, the clinical utilization of biomaterial-based scaffolds is constrained by their inadequate mechanical stren...
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Article
Mechanistic insights from inflammasome structures
Inflammasomes are supramolecular complexes that form in the cytosol in response to pathogen-associated and damage-associated stimuli, as well as other danger signals that perturb cellular homoeostasis, resulti...
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Open AccessAlterations of the bile microbiome is associated with progression-free survival in pancreatic ductal adenocarcinoma patients
Patients with pancreatic ductal adenocarcinoma (PDAC) display an altered oral, gastrointestinal, and intra-pancreatic microbiome compared to healthy individuals. However, knowledge regarding the bile microbiom...
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Open AccessSlit2–Robo4 signal pathway and tight junction in intestine mediate LPS-induced inflammation in mice
Sepsis is one of the most common clinical diseases, which is characterized by a serious and uncontrollable inflammatory response. LPS-induced inflammation is a critical pathological event in sepsis, but the un...
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Open AccessRapid improvement of grain appearance in three-line hybrid rice via CRISPR/Cas9 editing of grain size genes
Genetic editing of grain size genes quickly improves three-line hybrid rice parents to increase the appearance quality and yield of hybrid rice.
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Article
Electron Microscopic Map** of Mitochondrial Morphology in the Cochlear Nerve Fibers
To enable nervous system function, neurons are powered in a use-dependent manner by mitochondria undergoing morphological-functional adaptation. In a well-studied model system—the mammalian cochlea, auditory n...
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The value of ictal scalp EEG in focal epilepsies surgery: a retrospective analysis
To describe the association between preoperative ictal scalp electroencephalogram (EEG) results and surgical outcomes in patients with focal epilepsies.
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Article
Open AccessPlasma circulating tumor DNA unveils the efficacy of PD-1 inhibitors and chemotherapy in advanced gastric cancer
Programmed Death Receptor 1 (PD-1) inhibitors, when combined with chemotherapy, have exhibited notable effectiveness in enhancing the survival outcomes of patients afflicted with advanced gastric cancer. Howev...
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Article
Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Open AccessReal-world performance of HIV low viral load values in diagnosing acute HIV infection in a tertiary care hospital in Bei**g, China
Early diagnosis of HIV infection decreases the time from HIV diagnosis to viral suppression and reduces further HIV transmission. The Chinese Guidelines for the Diagnosis and Treatment of HIV/AIDS (2021 editio...
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Open AccessMetabolic syndrome parameters' variability and stroke incidence in hypertensive patients: evidence from a functional community cohort
Stroke is a common complication of hypertension, but the predictive value of metabolic syndrome parameters' variability on stroke risk in individuals with hypertension remains unclear. Therefore, our objective...
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Open AccessGenetic Effects of Grain Quality Enhancement in Indica Hybrid Rice: Insights for Molecular Design Breeding
Improving rice quality remains a crucial breeding objective, second only to enhancing yield, yet progress in quality improvement lags behind yield. The high temperature and ripening conditions in Southern Chin...