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Article
Open AccessCDK4/6 inhibition enhances T-cell immunotherapy on hepatocellular carcinoma cells by rejuvenating immunogenicity
Hepatocellular carcinoma (HCC) poses a significant clinical challenge, necessitating the integration of immunotherapeutic approaches. Palbociclib, a selective CDK4/6 inhibitor, has demon...
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Chapter and Conference Paper
Design of Water Ecological Cleaning Robot Based on Raspberry PI and OpenCV Visual Recognition
In this paper, a water ecological cleaning robot in the near water area is designed with Raspberry PI microcontroller as the core control. Through the OpenCV intelligent visual recognition module, the feature ...
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Article
Longitudinal beam dynamic design of 500 kW beam power upgrade for CSNS-II RCS
The accelerator of the China Spallation Neutron Source (CSNS) consists of an 80 MeV H- linac and a 1.6 GeV rapid cycling synchrotron (RCS). The design beam power is 100 kW, which has been reached. In the upgra...
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Article
Flow and mixing in a tube-in-tube millireactor with multiholes jet and twist tapes
A novel tube-in-tube millireactor with multiholes jet and twist tapes was designed and investigated for its excellent mixing, low price, and industrialization prospects. The inner tube fluid jets into the annu...
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Chapter and Conference Paper
Measurement and Adjustment Model of the Reception Ratio of “FAST” Reflector Panel
FAST is a radio telescope with the largest single-aperture and the highest resolution in the world built in China at present. In this paper, the adjustment of the reflective panel and the increase of receiving...
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Article
Open AccessMortalin/glucose-regulated protein 75 promotes the cisplatin-resistance of gastric cancer via regulating anti-oxidation/apoptosis and metabolic reprogramming
Platinum drug treatment is one of the most predominant chemotherapeutic strategies for patients with gastric cancer (GC). However, the therapeutic effect is less than satisfactory, largely due to the acquired ...
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Article
An on-chip intestine-liver model for multiple drugs absorption and metabolism behavior simulation
A double-layer microfluidic chip integrated with a hollow fiber (HF) was developed to reconstitute the intestine-liver functionality for studying the absorption and metabolism of combination drugs. Caco-2 cell...
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Article
Detection and differentiation of Japanese encephalitis virus genotype I and genotype III by reverse transcription loop-mediated isothermal amplification combined with restriction fragment length polymorphism
Japanese encephalitis (JE), which is a mosquito-borne arboviral infection, is the leading cause of viral encephalitis in Asian countries. The causative agent of JE is Japanese encephalitis virus (JEV), in whic...