6 Result(s)
within
Han-Seam Choi
Biomedicine
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Article
Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells
Iodothyronine deiodinase types I, II, and III (D1, D2, and D3, respectively), which constitute a family of selenoenzymes, activate and inactivate thyroid hormones through the removal of specific iodine moietie...
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Article
Benzo[k]fluoranthene-induced changes in miRNA-mRNA interactions in human hepatocytes
Toxicology studies assessing the risk of environmental toxicants in humans frequently use in vitro systems in combination with transcriptomics to characterize toxic responses. Thus far, changes have mostly been i...
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Article
Identification of genes induced by dibutyl phthalate in human thyroid follicular FTC-238 cells
Dibutyl phthalates (DBP) are widely used as plasticizers to soften and increase the flexibility of polyvinyl chloride plastics, although they can leach into the surrounding environment. Many studies have repor...
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Article
Gene expression analysis identifies DNA damage-related markers of benzo[a]pyrene exposure in HepG2 human hepatocytes
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is carcinogenic to humans. Although the environmental distribution and metabolism of BaP have been reported and many researchers are perform...
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Article
Analysis of differentially expressed genes by Mirex ‘persistent organic pollutant’ in HepG2 cells
Mirex is a bioaccumulative, persistent, and toxic pollutant. It is one of 12 priority persistent organic pollutants identified as requiring global action by the United Nations Environment Program (UNEP) Govern...
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Article
The optimal conditions for the estimation of DNA methylation levels using high throughput microarray derived DNA immunoprecipitation (MeDIP)-enrichment in human bloods
Genomic-wide map** of epigenetic changes is essential for understanding the mechanisms involved in chemical-induced gene regulation. The identification of DNA methylation patterns is a common procedure in th...
