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  1. No Access

    Article

    The need to investigate hyperuricemia as a factor in the onset of age-related macular degeneration

    Hung-Liang Pai, Han-Hsin Chang, David Pei-Cheng Lin in Eye (2021)

  2. Article

    Open Access

    Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model

    Hedgehog signalling has been implicated in prostate tumorigenesis in human subjects and mouse models, but its effects on transforming normal basal/stem cells toward malignant cancer stem cells remain poorly un...

    Han-Hsin Chang, Bo-Yie Chen, Chia-Yung Wu, Zih-Jay Tsao in Journal of Biomedical Science (2011)

  3. Article

    A mouse prostate cancer model induced by Hedgehog overexpression

    Hedgehog is a regulatory protein during embryonic development and its abnormal activation in adult tissues has been implicated in tumorigenesis within sites where epithelial–mesenchymal interactions take place...

    Bo-Yie Chen, David Pei-Cheng Lin, Jer-Yuh Liu, Han Chang in Journal of Biomedical Science (2006)

  4. No Access

    Article

    Influenza-B-virus-induced eye and brain malformations during early chick embryogenesis and localization of the viral RNA in specific areas

    Influenza is prevalent worldwide, and the teratogenic effects of influenza infection have been suspected to occur within the develo** central nervous system. We herein report the sequelae of influenza B vira...

    Bo-Yie Chen, Han-Hsin Chang, Hui-Ling Chiou in Journal of Biomedical Science (2004)

  5. Article

    Open Access

    Estimation of energy requirements for mechanically ventilated, critically ill patients using nutritional status

    There is very little information on what is considered an adequate energy intake for mechanically ventilated, critically ill patients. The purpose of the present study was to determine this energy requirement ...

    Mee-Nin Kan, Han-Hsin Chang, Woei-Fen Sheu, Chien-Hsiang Cheng in Critical Care (2003)

  6. No Access

    Article

    The status of plasma homocysteine and related B-vitamins in healthy young vegetarians and nonvegetarians

    Background: Exclusion of animal products and having only plant protein in vegetarian diets may affect the status of certain B-vitamins, and further cause the elevation of plasma homocysteine concentration. Aim: ...

    Yi-Chia Huang, Sue-Joan Chang, Yu-Ting Chiu in European Journal of Nutrition (2003)