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Article
Open AccessGenetic landscape and PD-L1 expression in Epstein–Barr virus-associated gastric cancer according to the histological pattern
Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) is a distinct molecular subtype of gastric cancer. This study aims to investigate genomic and clinicopathological characteristics of EBVaGC according...
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Article
Rebamipide for the Improvement of Gastric Atrophy and Intestinal Metaplasia: A Prospective, Randomized, Pilot Study
The presence of atrophic gastritis (AG) and intestinal metaplasia (IM) is associated with an increased risk of gastric cancer (GC). Thus, the development of new strategies to improve AG/IM is essential for red...
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Article
Open AccessIntratumoural PD-L1 expression is associated with worse survival of patients with Epstein–Barr virus-associated gastric cancer
This study investigated the clinical relevance and prognostic impact of the overall expression of programmed cell death protein ligand-1 (PD-L1) and programmed cell death protein ligand-2 (PD-L2), in patients ...
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Article
Open AccessSpontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat
Peripheral ameloblastic odontoma is a rare variant of odontogenic tumor occurring in the extraosseous region. The present report describes a spontaneous tumor in male Sprague-Dawley (SD) rats. The clinically c...
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Article
Endoscopic Resection as a First Therapy for Gastric Epithelial Atypia: Is It Reasonable?
Gastric atypical cell (GAC), an indefinite pathologic finding, often requires repeated biopsy or other diagnostic treatments, such as endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD),...
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Article
Phosphorylated AMP-activated protein kinase expression associated with prognosis for patients with gastric cancer treated with cisplatin-based adjuvant chemotherapy
The present study analyzed the expression of phosphorylated AMP-activated protein kinase (pAMPK), Fyn kinase, and pyruvate dehydrogenase kinase-1 (PDK-1) and their impact on the survival of patients with resec...
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Article
RIPK1 and CASP7 polymorphism as prognostic markers for survival in patients with colorectal cancer after complete resection
Since apoptosis plays a key role in cancer progression, the present study analyzed the polymorphisms of apoptosis-related genes and their impact on survival after curative resection in patients with colorectal...
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Article
Overexpression of the MUC2 gene through promoter hypomethylation in mucinous cell carcinomas and signet ring cell carcinomas of gastric cancer
Gastric carcinoma (GC) remains an important cause of mortality and morbidity in East Asia and the histological classification is still controversial, despite considerable understanding of the molecular nature ...
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Article
Endoscopic characteristics of gastric adenomas suggesting carcinomatous transformation
Currently, endoscopic resections, including endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), are widely performed for the management of gastric neoplasia. This study aimed to eval...
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Article
Gastric schwannomas: endosonographic characteristics
Gastric schwannomas are rare benign neurogenic mesenchymal tumors that are usually asymptomatic but can present with variable symptoms. We retrospectively reviewed the endosonographic features of four patients...
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Article
Perfluorooctanoic acid-induced hepatic toxicity following 21-day oral exposure in mice
Perfluorooctanoic acid (PFOA) is a member of the perfluoroalkyl acids that have wide commercial applications and is a widespread pollutant of toxicological importance that has been detected in environmental ma...
