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  1. No Access

    Article

    Overexpression of SERCA2 ATPaase in vascular smooth muscle cells treated with oxidized low density lipoprotein

    Oxidized low density lipoprotein (oxLDL) has been identified as a potentially important atherogenic factor. Atherosclerosis is characterized by the accumulation of lipid and calcium in the vascular wall. OxLDL...

    Hamid Massaeli, J. Alejandro Austria… in Molecular and Cellular Biochemistry (2000)

  2. No Access

    Chapter

    Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels

    Vascular lesion development is associated with an accumulation of extracellular matrix proteins within the vessel wall. Matrix metalloproteinases (MMPs) degrade these proteins. Conversely, oxidized low density...

    David Wilson, Hamid Massaeli… in Biochemistry of Diabetes and Atheroscleros… (2003)

  3. No Access

    Chapter

    Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat

    Clinically significant occlusive vascular lesions contain more extracellular matrix (ECM) proteins and lipid deposition than healthy vascular tissue. The events leading to this condition remain unresolved. One...

    David Wilson, Hamid Massaeli… in Biochemistry of Diabetes and Atheroscleros… (2003)

  4. No Access

    Article

    Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat

    Clinically significant occlusive vascular lesions contain more extracellular matrix (ECM) proteins and lipid deposition than healthy vascular tissue. The events leading to this condition remain unresolved. One...

    David Wilson, Hamid Massaeli, James C. Russell… in Molecular and Cellular Biochemistry (2003)

  5. No Access

    Article

    Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels

    Vascular lesion development is associated with an accumulation of extracellular matrix proteins within the vessel wall. Matrix metalloproteinases (MMPs) degrade these proteins. Conversely, oxidized low density...

    David Wilson, Hamid Massaeli, Grant N. Pierce… in Molecular and Cellular Biochemistry (2003)

  6. Article

    Gene Transfer of Prostaglandin Synthase Maintains Patency of the Newborn Lamb Arterial Duct

    In congenital heart disease with left- or right-sided obstruction, prostaglandin E (PGE)1 or PGE2 is infused to maintain ductus arteriosus (DA) patency. We hypothesized that transfection of the DA with PGE syntha...

    Tilman Humpl, Syed H E Zaidi, James Y Coe, Jennifer Russell… in Pediatric Research (2005)

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  7. No Access

    Chapter and Conference Paper

    Oxidation of Selected Lipids in Low Density Lipoprotein: Effects on Calcium Transients in Isolated Rabbit Cardiomyocytes

    When LDL is oxidized by a free radical generating system, both cholesterol and fatty acyl moieties within the LDL are modified. Oxidized low density lipoprotein (oxLDL) can induce alterations in the Ca2+ transien...

    Kan-zhi Liu, Hamid Massaeli, Bram Ramjiawan… in Advanced Bioactive Compounds Countering th… (2013)