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    Article

    Overexpression of SERCA2 ATPaase in vascular smooth muscle cells treated with oxidized low density lipoprotein

    Oxidized low density lipoprotein (oxLDL) has been identified as a potentially important atherogenic factor. Atherosclerosis is characterized by the accumulation of lipid and calcium in the vascular wall. OxLDL...

    Hamid Massaeli, J. Alejandro Austria in Molecular and Cellular Biochemistry (2000)

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    Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat

    Clinically significant occlusive vascular lesions contain more extracellular matrix (ECM) proteins and lipid deposition than healthy vascular tissue. The events leading to this condition remain unresolved. One...

    David Wilson, Hamid Massaeli, James C. Russell in Molecular and Cellular Biochemistry (2003)

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    Article

    Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels

    Vascular lesion development is associated with an accumulation of extracellular matrix proteins within the vessel wall. Matrix metalloproteinases (MMPs) degrade these proteins. Conversely, oxidized low density...

    David Wilson, Hamid Massaeli, Grant N. Pierce in Molecular and Cellular Biochemistry (2003)