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Article
Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat
Clinically significant occlusive vascular lesions contain more extracellular matrix (ECM) proteins and lipid deposition than healthy vascular tissue. The events leading to this condition remain unresolved. One...
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Article
Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels
Vascular lesion development is associated with an accumulation of extracellular matrix proteins within the vessel wall. Matrix metalloproteinases (MMPs) degrade these proteins. Conversely, oxidized low density...
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Article
Overexpression of SERCA2 ATPaase in vascular smooth muscle cells treated with oxidized low density lipoprotein
Oxidized low density lipoprotein (oxLDL) has been identified as a potentially important atherogenic factor. Atherosclerosis is characterized by the accumulation of lipid and calcium in the vascular wall. OxLDL...