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Article
The effects of ketogenic diet on metabolic and hormonal parameters in patients with polycystic ovary syndrome: a systematic review and meta-analysis of clinical trials
In recent years, using the ketogenic diet (KD) as a potential intervention for polycystic ovary syndrome (PCOS) has gained attention. Therefore, this study aimed to conduct a meta-analysis to determine the eff...
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Article
Open AccessIntegrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach
Glioblastoma is a highly heterogeneous disease, with variations observed at both phenotypical and molecular levels. Personalized therapies would be facilitated by non-invasive in vivo approaches for characteri...
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Article
Open AccessTocilizumab degradation via photo-catalytic ozonation process from aqueous
Following the advent of the coronavirus pandemic, tocilizumab has emerged as a potentially efficacious therapeutic intervention. The utilization of O3-Heterogeneous photocatalytic process (O3-HPCP) as a hybrid ad...
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Article
Ventilation system performance and its influence on indoor bioaerosols and thermal comfort in a COVID-19-designated hospital, Tehran
This cross-sectional experimental study was conducted in 24 active coronavirus wards in an advanced hospital in Tehran. The performance of the ventilation system was initially evaluated according to ASHRAE 62....
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Article
Open AccessCrosstalk between autophagy and insulin resistance: evidence from different tissues
Insulin is a critical hormone that promotes energy storage in various tissues, as well as anabolic functions. Insulin resistance significantly reduces these responses, resulting in pathological conditions, suc...
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Article
Correction: Effects of Ascophyllum nodosum-based Biostimulants on Improving Phytoextraction of Cadmium and Lead in Contaminated Soils
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Article
Changes of the Growth Rate of Wheat and Canola with Soil Amendments Application in Crop Rotation
Integrated nutrient management in crop rotation conditions (Canola-Soybean-Wheat) is important for farm management. Four years of field experiments were conducted to assess the effects of organic and inorganic...
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Article
Association of partial T2-FLAIR mismatch sign and isocitrate dehydrogenase mutation in WHO grade 4 gliomas: results from the ReSPOND consortium
While the T2-FLAIR mismatch sign is highly specific for isocitrate dehydrogenase (IDH)-mutant, 1p/19q-noncodeleted astrocytomas among lower-grade gliomas, its utility in WHO grade 4 gliomas is not well-studied...
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Article
Effects of Ascophyllum nodosum-based Biostimulants on Improving Phytoextraction of Cadmium and Lead in Contaminated Soils
The aim of this study was to improve phytoextraction of cadmium (Cd) and lead (Pb) from contaminated soils using Ascophillum nodosum extract (ANE). The experiment was designed in different groups: A-Planting of s...
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Article
Open AccessArtificial intelligence-based locoregional markers of brain peritumoral microenvironment
In malignant primary brain tumors, cancer cells infiltrate into the peritumoral brain structures which results in inevitable recurrence. Quantitative assessment of infiltrative heterogeneity in the peritumoral...
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Article
Optimization of parameters affecting the hydrothermal carbonization of wastewater treatment plant sewage sludge
The optimization of hydrothermal carbonization for sewage sludge (SS) was conducted in this study. The impact of three independent variables, namely biomass:water ratio (B/W) (10–30%), retention time (15–45 mi...
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Article
Open AccessThe University of Pennsylvania glioblastoma (UPenn-GBM) cohort: advanced MRI, clinical, genomics, & radiomics
Glioblastoma is the most common aggressive adult brain tumor. Numerous studies have reported results from either private institutional data or publicly available datasets. However, current public datasets are ...
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Article
Open AccessClinical measures, radiomics, and genomics offer synergistic value in AI-based prediction of overall survival in patients with glioblastoma
Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk assessment. Here, we investigate the additive val...
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Article
Blood Trace Element Status in Multiple Sclerosis: a Systematic Review and Meta-analysis
The aim of this meta-analysis was to investigate whether the blood concentrations of patients with multiple sclerosis (MS) are associated with those of the healthy control group in terms of trace elements incl...
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Article
A Systematic Review and Meta-analysis on Blood Lead Level in Opium Addicts: an Emerging Health Threat
This meta-analysis was conducted aiming to summarize the results obtained from the previous studies so that the effect of opium on blood lead levels (BLLs) can be investigated. Scopus, Embase, PubMed, and Web ...
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Article
Open AccessQuantification of tumor microenvironment acidity in glioblastoma using principal component analysis of dynamic susceptibility contrast enhanced MR imaging
Glioblastoma (GBM) has high metabolic demands, which can lead to acidification of the tumor microenvironment. We hypothesize that a machine learning model built on temporal principal component analysis (PCA) o...
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Article
Emergency hospital admissions for cardiovascular diseases attributed to air pollution in Tehran during 2016-2019
The burden of five main air pollutants, including CO, O3, NO2, SO2, and PM2.5, on the emergency department visits (EDVs) during January 2016–December 2019 due to all cardiovascular diseases was assessed in Teh...
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Article
Association of C677T (rs1081133) and A1298C (rs1801131) Methylenetetrahydrofolate Reductase Variants with Breast Cancer Susceptibility Among Asians: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis were conducted to investigate the association between methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with breast cancer (BC) in Asians. Syst...
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Chapter and Conference Paper
Estimating Glioblastoma Biophysical Growth Parameters Using Deep Learning Regression
Glioblastoma (GBM) is arguably the most aggressive, infiltrative, and heterogeneous type of adult brain tumor. Biophysical modeling of GBM growth has contributed to more informed clinical decision-making. However...
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Article
Open AccessLaboratory features of severe vs. non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis
More severe cases of COVID- 19 are more likely to be hospitalized and around one-fifth, needing ICU admission. Understanding the common laboratory features of COVID-19 in more severe cases versus non-severe pa...