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Article
Development and evaluation of a novel water-based pigment marker for radiation therapy skin marking
Skin marks are widely used in external radiation therapy to ensure the accuracy of the irradiation position. However, conventional skin markers contain harmful substance, so we developed an alternative skin ma...
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Article
Effectiveness of shielding materials against 177Lu gamma rays and the corresponding distance relationship
The purpose of this study is to determine the dose reduction of different shielding materials at various distances from a 177Lu photon radiation source.
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Article
Standardization of knowledge-based volumetric modulated arc therapy planning with a multi-institution model (broad model) to improve prostate cancer treatment quality
Purpose: To evaluate whether knowledge-based volumetric modulated arc therapy plans for prostate cancer with a multi-institution model (broad model) are clinically useful and effective as a standardization met...
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Article
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors
To clarify the dosimetric characteristics of a real-time variable shape rubber-containing tungsten (STR) bolus in a clinical plan and investigate the efficacy of the STR bolus in photon radiotherapy for keloid...
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Article
Open AccessMulti-institution model (big model) versus single-institution model of knowledge-based volumetric modulated arc therapy (VMAT) planning for prostate cancer
We established a multi-institution model (big model) of knowledge-based treatment planning with over 500 treatment plans from five institutions in volumetric modulated arc therapy (VMAT) for prostate cancer. T...
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Article
Open AccessFeasibility study of volumetric modulated arc therapy with Halcyon™ linac for total body irradiation
The use of total body irradiation (TBI) with linac-based volumetric modulated arc therapy (VMAT) has been steadily increasing. Helical tomotherapy has been applied in TBI and total marrow irradiation to reduce...
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Article
Dosimetric characteristics of a thin bolus made of variable shape tungsten rubber for photon radiotherapy
In this study, we aim to clarify the dosimetric characteristics of a real time variable shape rubber containing tungsten (STR) as a thin bolus in 6-MV photon radiotherapy. The percentage depth doses (PDDs) and...
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Article
Open AccessSimplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose...
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Article
Dosimetric evaluation with knowledge-based planning created at different periods in volumetric-modulated arc therapy for prostate cancer: a multi-institution study
Dosimetric evaluation and variation assessment were performed with two knowledge-based planning (KBP) models created at different periods for volumetric-modulated arc therapy (VMAT) for prostate cancer at five...
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Article
Feasibility of using tungsten functional paper as a thin bolus for electron beam radiotherapy
Containing 80% tungsten by weight, tungsten functional paper (TFP) is a radiation-shielding material that is lightweight, flexible, disposable, and easy to cut. Through experimental measurements and Monte Carl...
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Article
Plan complexity quantification of dual-layer multi-leaf collimator for volumetric modulated arc therapy with Halcyon linac
This study characterized the plan complexity of the dual-layer multi-leaf collimator (MLC) performance for volumetric modulated arc therapy (VMAT) in Halcyon. Plan complexity metrics were computed independentl...
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Article
Open AccessMechanical performance of a commercial knowledge-based VMAT planning for prostate cancer
This study clarified the mechanical performance of volumetric modulated arc therapy (VMAT) plans for prostate cancer generated with a commercial knowledge-based treatment planning (KBP) and whether KBP system ...
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Article
Open AccessEvaluation of multiple institutions’ models for knowledge-based planning of volumetric modulated arc therapy (VMAT) for prostate cancer
The aim of this study was to evaluate the performance of a commercial knowledge-based planning system, in volumetric modulated arc therapy for prostate cancer at multiple radiation therapy departments.
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Article
Comparison of dose accuracy between film and two-dimensional detectors in intensity-modulated radiation therapy
We constructed seven intensity-modulated radiation therapy (IMRT) treatment plans for prostate cancer (49 irradiation fields which contained seven randomly-sampled patients and seven fields) and evaluated the ...
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Article
Pharmacokinetic model of myocardial 99mTc-sestamibi washout
Technetium-99m sestamibi (99mTc-MIBI) scintigraphy has been reported to be a functional imaging tool for in vivo detection of mitochondrial dysfunction in myocardium and multidrug resistance-associated protein ex...
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Article
A feasibility study on reduction of the entrance-surface dose to neonates by use of a new digital mobile X-ray system
We investigated the neonatal entrance-surface dose (ESD) and doses of scattered radiation emitted by a digital mobile X-ray system. The system is equipped with a novel flat-panel detector and is used in the ne...
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Article
The impact of adenosine pharmacologic stress combined with low-level exercise in patients undergoing myocardial perfusion imaging (BIWAKO adenosine-Ex trial)
The combination of adenosine infusion with low-level exercise has become a common approach for inducing stress during stress myocardial perfusion imaging (MPI). We investigated stress MPI performed by combined...
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Article
Countermeasures against physical motion in schoolchildren requiring no sedation during rest and stress myocardial perfusion imaging with technetium-99m-tetrofosmin
For children, cardiac nuclear medicine imaging has not been widely used because of problems of physical motion, even in schoolchildren who require no sedation. In this study, rest–stress myocardial perfusion i...
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Article
The optimal cardiac phase for detecting the thrombi of the left atrial appendage on multi-slice computed tomography in patients with atrial fibrillation
We evaluated patients with atrial fibrillation (Af) to define the optimal phase for ECG-gated image reconstruction for multi-slice CT (MSCT) of the left atrial appendage (LAA). We performed MSCT scans in 37 pa...
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Article
New protocol of myocardial SPECT imaging with technetium-99m sestamibi for reducing the time interval between rest and adenosine stress phases
We have developed a new protocol of myocardial perfusion-gated single-photon emission computed tomography (SPECT), by use of technetium-99m sestamibi (MIBI), in which SPECT imaging at rest followed by SPECT im...
