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  1. Article

    Open Access

    GPR116 receptor regulates the antitumor function of NK cells via Gαq/HIF1α/NF-κB signaling pathway as a potential immune checkpoint

    NK cell is one of innate immune cells and can protect the body from cancer-initiating cells. It has been reported that GPR116 receptor is involved in inflammation and tumors. However, the effect of GPR116 recepto...

    Dandan Guo, Chenxu **, Yaoxin Gao, Haizhen Lin, Li Zhang, Ying Zhou… in Cell & Bioscience (2023)

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  2. Article

    Open Access

    Suppression of 4.1R enhances the potency of NKG2D-CAR T cells against pancreatic carcinoma via activating ERK signaling pathway

    Pancreatic carcinoma (PC) is one of the most common malignancies. Chimeric antigen receptor (CAR)-modified T cells has achieved remarkable efficacy in the treatment of hematological malignancies. However, lack...

    Yaoxin Gao, Haizhen Lin, Dandan Guo, Sijia Cheng, Ying Zhou, Li Zhang… in Oncogenesis (2021)

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  3. No Access

    Article

    Does Competition Lead to Agglomeration or Dispersion in EMR Vendor Decisions?

    We examine hospital Electronic Medical Record (EMR) vendor adoption patterns and how they relate to hospital market structure. As in many network technology adoption decisions, hospitals face countervailing in...

    Seth Freedman, Haizhen Lin, Jeffrey Prince in Review of Industrial Organization (2018)

  4. No Access

    Article

    Negligence and two-sided causation

    We extend the economic analysis of negligence and intervening causation to “two-sided causation” scenarios. In the two-sided causation scenario the effectiveness of the injurer’s care depends on some interven...

    Keith N. Hylton, Haizhen Lin, Hyo-Youn Chu in European Journal of Law and Economics (2015)