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Article
Open AccessUnlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway
STAM Binding Protein Like 1 (STAMBPL1), functions as a deubiquitinase (DUB) and plays a significant role in various types of cancers. However, its effect as a DUB participating in the HCC tumorigenesis and pro...
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Article
Open AccessSalmonellosis outbreak archive in China: data collection and assembly
Infectious disease outbreaks transcend the medical and public health realms, triggering widespread panic and impeding socio-economic development. Considering that self-limiting diarrhoea of sporadic cases is u...
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Article
Genome-wide association analysis of kernel nutritional quality in two natural maize populations
As one of the three staple crops, nutritional traits in maize are important for human and animal nutrition. Grain quality-related traits are closely related to grain commercial value. Understanding the genetic...
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Article
Single-incision plus one port laparoscopic right hemicolectomy with complete mesocolic excision and intracorporeal anastomosis
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Article
Up-regulating microRNA-214-3p relieves hypoxic–ischemic brain damage through inhibiting TXNIP expression
A list of microRNAs (miRs) has been referred to involve in the development of hypoxic–ischemic brain damage (HIBD). Based on that, we probed the concrete role of miR-214-3p regulating thioredoxin-interacting p...
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Article
Open AccessAspirin increases chemosensitivity of colorectal cancer cells and inhibits the expression of toll-like receptor 4
Chemotherapy resistance is an important bottleneck affecting the efficacy of chemotherapy in colon cancer. Therefore, improving the chemotherapy sensitivity of colorectal cancer cells is of great significance ...
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Article
Machine Learning of Histomorphological Features Predict Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer
We hypothesize that machine learning of histomorphological features can predict response to neoadjuvant therapy (NAT) in locally advanced rectal cancer (LARC).
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Article
Short-Term Outcomes of Tri-Staple Versus Universal Staple in Laparoscopic Anterior Resection of Rectal and Distal Sigmoid Colonic Cancer: A Matched-Pair Analysis
Anastomotic leakage is a serious complication in laparoscopic colorectal surgeries. To resolve this problem, a new stapling technology (Tri-staple) is developed. In this study, we aim to compare the short-term...
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Article
Open AccessCurrent status of and barriers to the treatment of advanced-stage liver cancer in China: a questionnaire-based study from the perspective of doctors
Liver cancer is a severe public health problem worldwide, and it creates a relatively higher disease burden in China than in the Western world. Despite achieving notable progress in China, potential difference...
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Stromal Organization as a Predictive Biomarker of Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer
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Article
Open AccessResearch on the Error Averaging Effect in A Rolling Guide Pair
By studying the effects of geometric precision on kinematic accuracy, an error map** model has been established, based on the hypothesis that a motion pair and its installation surface are rigid. However, wh...
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Article
Open AccessComplicated Gitelman syndrome and autoimmune thyroid disease: a case report with a new homozygous mutation in the SLC12A3 gene and literature review
Gitelman syndrome (GS) is an inherited autosomal recessive renal tubular disorder characterized by low levels of potassium and magnesium in the blood, decreased excretion of calcium in the urine, and elevated ...
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Article
Applying rotation-invariant star descriptor to deep-sky image registration
Image registration is a critical process of many deep-sky image processing applications. Image registration methods include image stacking to reduce noise or achieve long exposure effects within a short exposu...
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Article
Qualitative and quantitative analysis of misaligned electrode degradation when welding galvannealed steel
Electrode misalignment, induced from the flexibility of welding machine gun of spot welder or the potential poor fit-up, leads to the high tendency of expulsion and asymmetric nugget shape. Yet very few studie...
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Article
The reinforcement efficacy of nano- and microscale silica for extruded wood flour/HDPE composites: the effects of dispersion patterns and interfacial modification
The reinforcement efficacy of nano-silica particles for wood/plastic composites (WPCs) has been inconsistent in previous research. Accordingly, this systematic study was conducted to verify the reinforcement f...
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Article
Open AccessCO2 production, dissolution and pressure dynamics during silage production: multi-sensor-based insight into parameter interactions
Silage is a critical global feedstock, but is prone to aerobic deterioration. The dominant mechanism of O2 transport into silage remains unresolved. Here, multiple sensors tracked O2 and CO2, gas pressure (ΔP) be...
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Open AccessBioengineering of functional human induced pluripotent stem cell-derived intestinal grafts
Patients with short bowel syndrome lack sufficient functional intestine to sustain themselves with enteral intake alone. Transplantable vascularized bioengineered intestine could restore nutrient absorption. H...
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Article
Xeromorphic traits help to maintain photosynthesis in the perhumid climate of a Taiwanese cloud forest
Previous flux measurements in the perhumid cloud forest of northeastern Taiwan have shown efficient photosynthesis of the endemic tree species Chamaecyparis obtusa var. formosana even under foggy conditions in wh...
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Article
Short- and long-term outcomes of LigaSure versus conventional surgery for curative gastric cancer resection: a matched pair analysis
The LigaSure vessel sealing system allows dissection and hemostasis in a safe and quick way, and it has been reported to be an effective tool to shorten operative time and reduce intraoperative blood loss for ...
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Article
Laparoscopic Versus Open Incisional and Ventral Hernia Repair: A Systematic Review and Meta-analysis
Laparoscopic incisional and ventral hernia repair (LIVHR) is an alternative approach to conventional open incisional and ventral hernia repair (OIVHR). A consensus on outcomes of LIVHR when compared with OIVHR...
