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  1. Article

    Open Access

    Elevated expression of HIGD1A drives hepatocellular carcinoma progression by regulating polyamine metabolism through c-Myc–ODC1 nexus

    Hypoxia contributes to cancer progression through various molecular mechanisms and hepatocellular carcinoma (HCC) is one of the most hypoxic malignancies. Hypoxia-inducible gene domain protein-1a (HIGD1A) is t...

    Haixing Zhang, **aoran Li, Ziying Liu, Zimo Lin, Kuiyuan Huang… in Cancer & Metabolism (2024)

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  2. Article

    Open Access

    HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway

    The Hypoxia inducible gene domain family member 2A (HIGD2A) protein is indispensable for the assembly of the mitochondrial respiratory supercomplex, which has been implicated in cell proliferation and cell sur...

    Kuiyuan Huang, Ziying Liu, Zhanglian **e, **aoran Li… in Journal of Translational Medicine (2023)

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  3. No Access

    Article

    Remote sensing strategies to characterization of drought, vegetation dynamics in relation to climate change from 1983 to 2016 in Tibet and **njiang Province, China

    Due to various land cover changes, vegetation dynamics, and climate, drought is the most complex climate-related disaster problem in Tibet and **njiang, China. The purpose of the present study is to analyze th...

    Haixing Zhang, Shahzad Ali, Qi Ma, Liang Sun… in Environmental Science and Pollution Resear… (2021)

  4. No Access

    Article

    Simulation of micro-milling Inconel 718 considering scale effect

    To study the scale effect during micro-milling process, we establish a modified Johnson-Cook (JC) constitutive model to describe the strengthening behavior of materials on microscale based on the theory of str...

    **aohong Lu, Zhenyuan Jia, Haixing Zhang… in The International Journal of Advanced Manu… (2020)

  5. No Access

    Article

    Cutting parameters optimization for MRR under the constraints of surface roughness and cutter breakage in micro-milling process

    Selection of cutting parameters in micro-milling operations is essential for improving machining efficiency and quality, and prolonging the micro-milling tool life. The increase of material removal rate (MRR) ...

    **aohong Lu, Haixing Zhang, Zhenyuan Jia… in Journal of Mechanical Science and Technolo… (2018)

  6. No Access

    Article

    Floor surface roughness model considering tool vibration in the process of micro-milling

    The high quality of the micro-machined surface is the basic for promoting micro-milling technology, so the understanding of surface forming mechanism and the relationship between micro-milling parameters and t...

    **aohong Lu, Haixing Zhang, Zhenyuan Jia… in The International Journal of Advanced Manu… (2018)

  7. Article

    Open Access

    Prenatal ketamine exposure causes abnormal development of prefrontal cortex in rat

    Ketamine is commonly used for anesthesia and as a recreational drug. In pregnant users, a potential neurotoxicity in offspring has been noted. Our previous work demonstrated that ketamine exposure of pregnant ...

    Tianyun Zhao, Chuanxiang Li, Wei Wei, Haixing Zhang, Daqing Ma… in Scientific Reports (2016)

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