-
Article
Recent progress of metal halide perovskite materials in heterogeneous photocatalytic organic reactions
Photocatalytic technology is widely regarded as an important way to utilize solar energy and achieve carbon neutrality, which has attracted considerable attentions in various fields over the past decades. Meta...
-
Article
Open AccessProphylactic donor-derived CD19 CAR-T cell infusion for preventing relapse in high-risk B-ALL after allogeneic hematopoietic stem cell transplantation
-
Article
Open AccessNicotinamide Mononucleotide improves oocyte maturation of mice with type 1 diabetes
The number of patients with type 1 diabetes rises rapidly around the world in recent years. Maternal diabetes has a detrimental effect on reproductive outcomes due to decreased oocyte quality. However, the str...
-
Article
Modified EASIX scores predict severe CRS/ICANS in patients with acute myeloid leukemia following CLL1 CAR-T cell therapy
Chimeric antigen receptor T (CAR-T) cell therapy targeting CLL1 has been considered a potent weapon for patients with acute myeloid leukemia (AML). This study aims to evaluate the efficacy and toxicity of CLL1...
-
Article
Co-pyrolysis behavior of polylactic acid and biomass from heated tobacco products
In this study, the co-pyrolysis behavior of waste tobacco (WT) and polylactic acid (PLA) from heated tobacco products (HTPs) was investigated by TG, TG-FTIR, and Py-GC/MS in order to reveal the synergistic mec...
-
Article
Open AccessCornin protects against cerebral ischemia/reperfusion injury by preventing autophagy via the PI3K/Akt/mTOR pathway
Ischemia stroke is the leading cause of disability, which is a consequence of vascular occlusion. The purpose of this study is to investigate the effect of cornin which is isolated from the fruit of Verbena of...
-
Article
Feasibility of endoscopic endonasal resection of intrinsic third ventricular craniopharyngioma in adults
Intrinsic third ventricular craniopharyngiomas (IVCs) are usually considered as a contraindication of endoscopic endonasal approach (EEA). The aim of this study is to evaluate the safety and feasibility of EEA...
-
Article
Open AccessIncidence and risk factors for early pregnancy loss in women with first pregnancy undergoing in vitro fertilization-embryo transfer
This study aimed to explore the incidence and influencing factors for early pregnancy loss (EPL) in infertility patients with first pregnancy undergoing in vitro fertilization (IVF) embryo transfer cycles in J...
-
Article
A novel β2-AR agonist, Higenamine, induces β-arrestin-biased signaling
The biased ligands in G protein-coupled receptors (GPCRs) have opened new avenues for develo** safer and more effective drugs. However, the identification of such biased ligands as drug candidates is highly ...
-
Article
Open AccessGeneration of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver
Mice with humanized livers are important models to study drug toxicology testing, development of hepatitis virus treatments, and hepatocyte transplantation therapy. However, the huge difference between mouse a...
-
Chapter and Conference Paper
Decision-Making Framework of Supply Chain Service Innovation Based on Big Data
Information and communication technologies related to big data have been widely used in various fields. Global well-known enterprises obtain various structured data through big data platforms and quickly find ...
-
Article
A radioiodinated FR-β-targeted tracer with improved pharmacokinetics through modification with an albumin binder for imaging of macrophages in AS and NAFL
The formation of advanced plaques, which is characterized by the uninterrupted aggregation of macrophages with high expression of folate receptor-β (FR-β), is observed in several concomitant metabolic syndrome...
-
Article
Open AccessCD19 CAR-T cell treatment conferred sustained remission in B-ALL patients with minimal residual disease
The persistence or recurrence of minimal residual disease (MRD) after chemotherapy predicts relapse of B-cell acute lymphoblastic leukemia (B-ALL). CD19-directed chimeric antigen receptor T (CD19 CAR-T) cells ...
-
Article
Effect of support morphology on the activity and reusability of Pd/SiO2 for NBR hydrogenation
Silica hollow microspheres with moonscape-like rough surface (RS) and macroporous surface (MS) have been controllably synthesized by a water–oil–water three-phase emulsion method, which are used as supports of...
-
Article
Open AccessApplication of endoscopic endonasal approach in skull base surgeries: summary of 1886 cases in a single center for 10 consecutive years
Endonasal endoscopic skull base surgery has undergone rapid technological developments and is now widely performed, but its strengths and weaknesses deserve further investigation and deliberation. This study w...
-
Article
Open AccessSomatic SF3B1 hotspot mutation in prolactinomas
The genetic basis and corresponding clinical relevance of prolactinomas remain poorly understood. Here, we perform whole genome sequencing (WGS) on 21 patients with prolactinomas to detect somatic mutations an...
-
Article
Open Access5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease
The 5-hydroxymethylcytosine (5hmC) DNA modification is an epigenetic marker involved in a range of biological processes. Its function has been studied extensively in tumors, neurodegenerative diseases, and ath...
-
Chapter and Conference Paper
Research and Development of the Detection Robot in Pipeline Based on Electromagnetic Holography
It is important of the detection equipment and technology in the pipeline which means to prevent pipeline accidents before they occur. In this paper, an electromagnetic holography detection robot for nondestru...
-
Chapter and Conference Paper
Design and Validation of Three-Axis High Definition Magnetic Flux Leakage Detection Robot for Oil/Gas Pipelines
A large number of oil and gas pipeline leakage accidents from domestic and overseas showed that the main reasons for threatening the safety of pipeline operation were corrosions, cracks, weld joints and mechan...
-
Article
Molecular imaging of advanced atherosclerotic plaques with folate receptor-targeted 2D nanoprobes
Vulnerable atherosclerotic plaques are responsible for most cardiovascular diseases (CVDs). Folate receptor (FR) positive activated macrophages were thought to be a prominent component in the development of vu...
