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  1. Article

    Open Access

    A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer

    There are few effective treatments for small cell lung cancer (SCLC) underscoring the need for innovative therapeutic approaches. This study focuses on exploiting telomerase, a critical SCLC dependency as a th...

    Buse Eglenen-Polat, Ryan R. Kowash, Hai-Cheng Huang, Silvia Siteni in Nature Communications (2024)

  2. Article

    Open Access

    Autophagy Promotes Peripheral Nerve Regeneration and Motor Recovery Following Sciatic Nerve Crush Injury in Rats

    Autophagy maintains cellular homeostasis by stimulating the lysosomal degradation of cytoplasmic structures, including damaged organelles and dysfunctional proteins. The role of autophagy in the renewal and re...

    Hai-cheng Huang, Li Chen, Hai-xing Zhang, Sheng-fa Li in Journal of Molecular Neuroscience (2016)