51 Result(s)

Article

Liquordiagnostik bei CT-negativer Subarachnoidalblutung

Die Diagnostik CT-negativer Subarachnoidalblutungen (SAB) stellt eine besondere klinische Herausforderung dar. Die Lumbalpunktion mit Liquordiagnostik ist hierbei die diagnostische Methode der Wahl. Die Diagno...

H. Tumani, A. Petzold, M. Wick, H.-J. Kühn, M. Uhr, M. Otto, A. Regeniter… in Der Nervenarzt (2010)

Article

Morbus Wilson

Der Morbus Wilson ist eine autosomal-rezessiv vererbte Kupferstoffwechselstörung, die mit neurologischen Symptomen und Leberschädigung unterschiedlichen Ausmaßes einhergeht. Das betroffene Gen ATP7B kodiert für e...

Dr. D. Huster, H.-J. Kühn, J. Mössner, K. Caca in Der Internist (2005)

Article

Neurosyphilis oder Neuroborreliose

Es werden die infektionsserologischen Daten von 22 Patienten mit dem Verdacht auf das Vorliegen einer Neurosyphilis vorgestellt. In zwei Fällen wurde der Verdacht nicht bestätigt, in 20 Fällen eine Neurosyphil...

Dr. R. Blatz, H.-J. Kühn, W. Hermann, M. Rytter, A. C. Rodloff in Der Nervenarzt (2005)

Article

Expression patterns of erythropoietin and its receptor in the develo** midbrain

The expression patterns of erythropoietin (EPO) and its receptor (EPOR) were investigated in the midbrain and in adjacent parts of the synencephalon and hindbrain of embryonic C57Bl mice. On embryonic (E) day ...

W. Knabe, F. Knerlich, S. Washausen, T. Kietzmann, A. L. Sirén… in Anatomy and Embryology (2004)

Article

Investigation of fine-motor disturbances in Wilson's disease

Patients suffering from Wilson's disease (WD) can be divided into two main subgroups: neurologic and nonneurologic WD. We measured passive and active fine-motor abilities of 37 WD patients and 24 randomly sel...

W. Hermann, T. Villmann, F. Grahmann, H.J. Kühn, A. Wagner in Neurological Sciences (2003)

Article

Comparison of clinical types of Wilson's disease and glucose metabolism in extrapyramidal motor brain regions

In Wilson's disease a disturbed glucose metabolism especially in striatal and cerebellar areas has been reported. This is correlated with the severity of extrapyramidal motor symptoms (EPS). These findings ar...

W. Hermann, H. Barthel, S. Hesse, F. Grahmann, H.-J. Kühn… in Journal of Neurology (2002)

Article

The earliest invasion of macrophages into the develo** brain and eye of the tree shrew Tupaia belangeri

The earliest occurrence of macrophages was investigated in the brain and optic anlagen of the tree shrew Tupaia belangeri. Nineteen serially sectioned embryos, belonging to five phases of programmed neuroepitheli...

Wolfgang Knabe, H.-J. Kuhn in Anatomy and Embryology (1999)

Article

Disk formation in retinal cones of Tupaia belangeri (Scandentia)

Existing hypotheses on the mode of disk formation in the photoreceptor cells of mammals appear to be incompatible: (1) plasma membranes of adjacent evaginations form a disk which, subsequently, is internalized...

Wolfgang Knabe, H.-J. Kuhn in Cell and Tissue Research (1998)

Article

Ciliogenesis in photoreceptor cells of the tree shrew retina

 Transmission electron microscopy of the retinal cones from several prenatal, young postnatal and adult tree shrews (Tupaia belangeri) reveals that the centrioles, from which the ciliary precursors of the outer s...

Wolfgang Knabe, H.-J. Kuhn in Anatomy and Embryology (1997)

Chapter and Conference Paper

Continuous Filtration of Cerebrospinal Fluid (CSF-Filtration) in Fulminant Bacterial Meningitis — A New Adjuvant Therapeutic Strategy?

The introduction of antibiotics resulted in a reduced mortality rate in bacterial meningitis which, however, remained stable at 5–30% in the last 40 years, despite the development of new antibiotics [ 1, 10] ....

P. Kalischewski, D. Schneider, H. J. Kühn in Anaesthesia, Pain, Intensive Care and Emer… (1997)

Article

Zur Meßsicherheit der oszillometrischen Blutdruckmeßgeräte Dinamap 1846 und HP M-1008B

G. Papadopoulos, S. Mieke, H.-J. Kuhn, C. Apenburg in Der Anaesthesist (1996)

Chapter

The Stress-Strain Behaviour of IN738LC under Thermomechanical Uni- and Multiaxial Fatigue Loading

High temperature components such as cooled or uncooled first stage turbine blades are subjected to triaxial stress fields, mainly induced by constrained thermal strain fields during service. The steepest tempe...

J. Meersmann, J. Ziebs, H.-J. Kühn… in Fatigue under Thermal and Mechanical Loadi… (1996)

Article

Stretch-induced increase in the Ca²⁺ sensitivity of myofibrillar ATPase activity in skinned fibres from pig ventricles

The increase in force development in the heart with increase in end-diastolic pressure (Frank-Starling mechanism) has been ascribed to an increase in contractile responsiveness of the myofibrils to calcium. We...

H. J. Kuhn, C. Bletz, J. C. Rüegg in Pflügers Archiv (1990)

Article

Abstracts of the XVIII European Conference on Muscle and Motility

V. P. Nesterov, U. Peiper, J. Hiller… in Journal of Muscle Research & Cell Motility (1990)

Article

Myopathy with mitochondrial abnormalities and rimmed vacuoles

A man of 44 years suffering from an exercise-induced neuromuscular disease with mitochondrial abnormalities and rimmed vacuoles is reported. The mitochondrial abnormalities and rimmed vacuoles (autophagic vacu...

J. Lehmann, J. Ziegan, G. Oertel, J. Lößner, H. -J. Kühn in Acta Neuropathologica (1986)

Article

The effect of MgATP on forming and breaking actin-myosin linkages in contracted skinned insect flight muscle fibres

At neutral pH, fully Ca²⁺ -activated glycerinated dorsal longitudinal fibre bundles fromLethocerus indicus contract under isometric conditions and respond to release by deactivation, i.e. quick release causes a d...

H. J. Kuhn, C. Bletz, K. Güth, J. C. Rüegg in Journal of Muscle Research & Cell Motility (1985)

Chapter

Tension Transients in Skinned Muscle Fibres of Insect Flight Muscle and Mammalian Cardiac Muscle: Effect of Substrate Concentration and Treatment with Myosin Light Chain Kinase

Glycerinated single fibres from the dorsal longitudinal muscle of Lethocerus maximus were isometrically contracted in MgATP-salines (10 μM Ca²⁺; 1.5 mM Mg²⁺; pH 6.7: 22°C and 20 mM PEP; 100 U/ml pyruvate kinase)....

J. C. Rüegg, H. J. Kuhn, K. Gūth, G. Pfitzer… in Contractile Mechanisms in Muscle (1984)

Article

Buchbesprechungen

Rhea Lüst, K. Keil, S. Brandt, R. Hoppe, G. Tölg, K. Starke… in Naturwissenschaften (1982)

Article

The effect of Ca ions on the kinetics of actin-myosin interactions in glycerinated cray-fish muscle fibres

H. J. Kuhn, S. Pferrer, K. Güth in Pflügers Archiv (1982)