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Chapter and Conference Paper
The Love Wave Immunosensor for Detecting the Pneumonia Biomarker Procalcitonin (PCT)
Pneumonia refers to infectious inflammation of the pulmonary parenchyma caused by bacterial, viral, and other pathogens. The early screening and identification of the pathogen is essential to the treatment for...
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Article
Open AccessCOPB2: a transport protein with multifaceted roles in cancer development and progression
The Coatomer protein complex subunit beta 2 (COPB2) is involved in the formation of the COPI coatomer protein complex and is responsible for the transport of vesicles between the Golgi apparatus and the endopl...
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Article
ST8SIA1 inhibition sensitizes triple negative breast cancer to chemotherapy via suppressing Wnt/β-catenin and FAK/Akt/mTOR
Chemoresistance is the major cause of therapeutic failure in triple negative breast cancer (TNBC). In this work, we investigated the molecular mechanism for the development of TNBC chemoresistance.
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Article
QTL map** for adult-plant resistance to powdery mildew in Chinese elite common wheat Chuanmai104
Powdery mildew, caused by Blumeria graminis f. sp. tritici, is a major fungal disease of wheat worldwide. The economic and environmentally friendly strategy is develo** the wheat varieties with resistance to po...
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Chapter and Conference Paper
Is Communicating Material an Intelligent Product Instantiation? Application to the McBIM Project
Information and communication technologies, like Wireless Sensor Networks (WSN) allow to creating new objects made of materials including micro-elements able of data sensing, storing, processing, and communica...
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Article
Reply to ‘Body mass index and the risk of all-cause mortality among patients with nonvalvular atrial fibrillation: a multicenter prospective observational study in China; methodological issues’
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Article
Body mass index and the risk of all-cause mortality among patients with nonvalvular atrial fibrillation: a multicenter prospective observational study in China
High body mass index (BMI) is associated with increased incident atrial fibrillation (AF) and mortality rate. In patients presenting with nonvalvular AF (NVAF), the prognostic relevance of BMI remains unclear.
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Article
Highly efficient synthesis of quinoxaline derivatives catalized by iridium complex
A novel iridium complex was used to catalyze a mild reaction of phenylenediamine with propanediol that led to formation of quinoxaline derivatives with moderate to high yields. The reaction diemonstrated stron...
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Article
Characterization of the Microbial Communities in the Ant Lion Euroleon coreanus (Okamoto) (Neuroptera: Myrmeleontidae)
Euroleon coreanus (Okamoto) is widely distributed in China, and the larval stage can be treated as traditional Chinese medicine. However, the host-bacterium relationship remains unexplore...
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Article
The Cu-catalyzed C–P coupling of phosphonate esters with arylboronic acids
Copper-catalyzed C–P cross coupling of phosphonate esters with arylboronic acids has been developed. The reaction provided an efficient method for aryl phosphonates under mild conditions.
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Article
Determination of the toxicity of herb preparations of the traditional Chinese medicine with a multisensor system
Preparations based on medicinal herbs used in the traditional Chinese medicine to cure and make a prophylactic treatment of a wide variety of diseases wee studied. The goal of the study was to assess the capac...
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Article
Open AccessmiR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop
The effective mechanisms of microRNAs (miRNAs) functions as oncogenes or tumour suppressors in human hepatocellular carcinoma (HCC) are still obscure. Here, we investigated the function and expression of miR-1...
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Article
Distinct roles of RIP1–RIP3 hetero- and RIP3–RIP3 homo-interaction in mediating necroptosis
Necroptosis is mediated by a signaling complex called necrosome, containing receptor-interacting protein (RIP)1, RIP3, and mixed-lineage kinase domain-like (MLKL). It is known that RIP1 and RIP3 form heterodim...
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Article
Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation
Desmoglein 3 (Dsg3), the pemphigus vulgaris antigen, has recently been shown to be upregulated in squamous cell carcinoma (SCC) and has been identified as a good tumor-specific marker for clinical staging of c...
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Article
Open AccessLoss of TACSTD2 contributed to squamous cell carcinoma progression through attenuating TAp63-dependent apoptosis
Tumor-associated calcium signal transducer 2 (TACSTD2), a calcium signal transducer, is universally expressed in stratified squamous epithelia of many organs, including skin, esophagus and cervix. Although TAC...
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Article
A simulation study of cadaveric liver allocation with a single-score patient prioritization formula
In this article, we present a simulation study on prioritizing patients for receiving scarce cadaveric liver donations. We propose a ranking formula that combines the four criteria commonly used for prioritizi...
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Chapter and Conference Paper
Novel Algorithm to Suppress Random Pulse Interference in Spikes
Spikes detection and sorting play an important role in study of neural information coding. Spikes were generally obtained by threshold detection after filtered in traditional detection, which failed to suppres...
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Article
Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2
We report the characterization of BMS-911543, a potent and selective small-molecule inhibitor of the Janus kinase (JAK) family member, JAK2. Functionally, BMS-911543 displayed potent anti-proliferative and pha...
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Article
Open AccessAnalysis of BENCHMRK 1 & 2 using PhenoSense® assay for darunavir (DRV/r) resistance and exploration of functional monotherapy with RAL vs DRV
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Article
A structural mechanics approach for predicting the mechanical properties of carbon nanotubes
Based on molecular mechanics, a structural mechanics model of carbon nanotubes (CNTs) was developed with special consideration given to the bending stiffness of the graphite layer. The potentials associated wi...