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Determinants of Outer Membrane Protein Sorting and Topology in Mitochondria

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    Structural and mechanistic basis of Parl activity and regulation

    The mitochondrial rhomboid protease Parl governs apoptosis, morphology, metabolism and might be implicated in Parkinson's disease, but the structural basis of its activity and complex regulation remain unknown...

    D V Jeyaraju, H M McBride, R B Hill, L Pellegrini in Cell Death & Differentiation (2011)

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