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The works of Dirk Durrer (1918–1984)
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Article
Open AccessUnmappable ventricular tachycardia after an old myocardial infarction. Long-term results of substrate modification in patients with an implantable cardioverter defibrillator
The frequent occurrence of ventricular tachycardia can create a serious problem in patients with an implantable cardioverter defibrillator. We assessed the long-term efficacy of catheter-based substrate modifi...
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Article
12-Kanal-Elektrokardiogramm
Das 12-Kanal-Oberflächen-EKG ist von großer Bedeutung für die Diagnostik von Rhythmusstörungen und für das akute Koronarsyndrom. Supraventrikuläre Tachykardien (SVT) wie Sinustachykardien, atriale Tachykardien...
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Article
Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart
We report a novel real-time imaging model to visualize apoptotic membrane changes of single cardiomyocytes in the injured heart of the living mouse, using fluorescent labeled annexin-V. Annexin-V binds to exte...
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Chapter
Supraventricular tachycardia with left aberrant conduction due to retrograde invasion into the left bundle branch
A description is given of a patient with an atrioventricular nodal tachycardia with left aberrant conduction changing into nonaberrant conduction after a ventricular premature beat. Functional left bundle-bran...
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Chapter
Atrial tachycardia facilitating initiation of ventricular tachycardia
A 17-year-old male was studied because of clinically documented tachycardias showing narrow and wide QRS complexes. He was found to suffer from an atrial and a ventricular tachycardia. It was demonstrated that...
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Chapter
Clinical presentation and prognosis of left main coronary artery disease in the 1980s
Clinical presentation and course were studied in 127 consecutive patients with angiographically proven left main coronary artery disease. Mean age was 62 (37-79) years. Thirteen patients (10%) had no history o...
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Chapter
Molecular genetics of inherited long QT syndromes
Unravelling the molecular cause of QT prolongation is one of the most exciting contributions of molecular biology to clinical cardiology in the last decade. Not only have mutations in four different genes been de...
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Chapter
The role of premature beats in the initiation and the termination of supraventricular tachycardia in the Wolff-Parkinson-White syndrome
In four patients with WPW syndrome atrial and ventricular premature beats were induced and the changes in form of the ventricular and atrial complexes were studied. Results indicate that, depending upon the ti...
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Chapter
Epilogue
The studies reported in this book almost unanimously demonstrate that, in patients with symptomatic coronary atherosclerosis, lipid lowering retards progression of the disease process and may even lead to regr...
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Chapter and Conference Paper
When to Treat Arrhythmias in Heart Failure?
Clinical medicine is characterized by a continuous process of decision making based on optimal diagnostic information leading to the most appropriate therapeutic approach. Very important in this process is ind...
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Book
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Chapter
The Electrocardiogram in Pulmonary Embolism
Pulmonary embolism is a frequently clinically unrecognized entity [1]. Some studies suggest-that it might be the most common cause of death among hospitalized patients, either as its major or sole cause, or as...
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Chapter
The Differentiation between Ventricular Tachycardia and Supraventricular Tachycardia with Aberrant Conduction: The Value of the 12-Lead Electrocardiogram
The correct diagnosis of the site of origin of a regular tachycardia with a wide QRS (≥0.12 s) complex continues to be an exciting challenge. It is not only an exercise in electrocardiography, but also a decis...
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Chapter
The Electrocardiogram in Digitalis Intoxication
Digitalis intoxication is one of the most common adverse drug reactions and continues to be frequently fatal. In the Netherlands approximately 2% of the population are regular users of the drug [1] and in 1976...
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Chapter
Assessment of the Value of Electrocardiographic Signs for Myocardial Infarction in Left Bundle Branch Block
Various electrocardiographic criteria (Cabrera, Chapman, initial notching of QRS, RS configuration V6, abnormal Q waves, ST-segment elevation, positive T waves) have been reported to be of value for the diagnosis...
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Chapter
The Value of the Electrocardiogram in Diagnosing Site of Origin and Mechanism of Supraventricular Tachycardia
Developments in the field of clinical cardiac electrophysiology during the past decade have made it possible to determine the site of origin and frequently the mechanism of most supraventricular tachycardias [...
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Book
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Chapter
Sudden Death in the Wolff-Parkinson-White Syndrome
In the human heart the refractory period of the AV node protects the ventricle against supraventricular rhythms with a very high rate. In the presence of an accessory atrio-ventricular (AV) pathway the ventric...
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Chapter and Conference Paper
Preoperative Localization of Bypass Tract(s) in the Wolff-Parkinson-White Syndrome
In 1967 Durrer and Roos (1) showed by epicardial excitation map** that an accessory atrioventricular connection was present in patients with the Wolff-Parksinson-White electrocardiogram. In the same year sti...
