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Chronic myeloproliferative diseases with concurrent BCR–ABL junction and JAK2V617F mutation
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Genotype and phenotype of a new 2-bp deletion of hMSH2 at codon 233
Germline mutations within mismatch repair genes, such as hMSH2, hMLH1, and hMSH6, have been shown to be the hallmark of the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome. The spectrum of tumors a...
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Scientific Proceedings Second International Symposium on Cytostatic Drug Resistance
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The relationship between nuclear DNA content in salivary gland tumors and prognosis
Differences in prognosis between salivary gland mucoepidermoid tumors and acinic cell tumors were compared by means of conventional histopathological grading and nuclear DNA content which was assessed cytochem...
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Article
Cytokines and pancreatic cancer
Ten xenotransplants of human gastrointestinal carcinomas (eight human pancreatic carcinomas) were assayed for their sensitivity to human rIFN-7 and human rTNF-a in nude mice. Both substances demonstrated a dos...
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Cytokines and pancreatic cancer the effect of rIFN-γ, HuLelFN, rTNF-α, and LAK-cells on pancreatic and other gastrointestinal tumors in vitro
A panel of 10 digestive tract carcinoma cell lines (6 pancreatic carcinomas) was assayed for their sensitivity to HuLelFN, human rIFN-7, rTNF-a and allogeneic human LAK-cells in vitro. In addition, a combinati...
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Article
Establishment of primary cell cultures: Experiences with 155 cell strains
Cell culture systems allow the examination of cell populations in a functional state. To simulate in vivo conditions as closely as possible freshly established cell strains are superior to permanent cell lines...
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Antigen detection by the monoclonal antibodies CA 19-9 and CA 125 in normal and tumor tissue and patients' sera
The tumor markers CA 19-9 and CA 125 defined by the monoclonal antibodies 19-9 and OC 125 were investigated with respect to organ specificity and tumor sensitivity. Normal and tumor tissue specimens, and blood...
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Chemosensitivity testing in proliferating monolayer cell cultures of malignant tumors
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Monitoring ovarian carcinoma with CA 125, CA 19–9, CA 15–3 and CEA in serum, ascites and tumor tissue
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Effectiveness of ifosfamid (IF) on human tumor cells in culture