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Open AccessMetabolomic associations of impaired awareness of hypoglycaemia in type 1 diabetes
This study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20–40% of individuals with type 1 diabetes. The exact pathophysiology is unclear, therefore we sou...
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De virtuele diabeteskliniek in een stroomversnelling?
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Zes vragen over zorgvernieuwing in diabeteszorg: het value-based healthcare-model in de praktijk
Op 11 mei ontving Diabeter de Value-Based Healthcare Prize 2017. Diabeter heeft sinds de oprichting in 2006 value-based healthcare (VBHC) toegepast en de zes onderdelen hiervan die waarde toevoegen voor de patiën...
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Chapter
35 Diabetes mellitus
Diabetes mellitus is een aandoening met diverse oorzaken die gekarakteriseerd wordt door een chronische hyperglykemie ten gevolge van een absoluut (productie) of relatief (werking) tekort aan insuline of door ...
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Circulating semicarbazide-sensitive amine oxidase is raised both in Type I (insulin-dependent), in Type II (non-insulin-dependent) diabetes mellitus and even in childhood Type I diabetes at first clinical diagnosis
Plasma semicarbazide-sensitive amine oxidase is raised in patients with Type I (insulin-dependent) diabetes mellitus. It has been suggested that this enzyme is involved in the development of microvascular dam...
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Islet cell cytoplasmic antibody reactivity in midgestational human fetal pancreas
The reactivity of islet cell cytoplasmic antibodies (ICA)-positive and ICA-negative sera of recent onset type 1 diabetic patients was studied in human fetal pancreata of 12–18 weeks' gestation and compared wit...
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Value of antibodies to GAD65 combined with islet cell cytoplasmic antibodies for predicting IDDM in a childhood population
The value of a test for islet cell cytoplasmic antibodies together with a test for GAD65 antibodies to predict the subsequent development of diabetes over a period of 11.5 years was assessed in an open childhood ...
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Enrichment of Beta cells from the human fetal pancreas by fluorescence activated cell sorting with a new monoclonal antibody
The aim of this study was to produce an antibody reactive to the surface of endocrine pancreatic cells and use this antibody for the purification of endocrine cells from the human fetal pancreas by fluorescenc...