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    Article

    Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies

    The nuclear export receptor, Exportin 1 (XPO1), mediates transport of growth-regulatory proteins, including tumor suppressors, and is overactive in many cancers, including chronic lymphocytic leukemia (CLL), a...

    Z A Hing, H Y J Fung, P Ranganathan, S Mitchell, D El-Gamal, J A Woyach… in Leukemia (2016)