Skip to main content

7 Result(s)

within H Uchino Remove this filter Neurology Remove this filter

and

  1. No Access

    Chapter and Conference Paper

    Search for novel gene markers of traumatic brain injury by time differential microarray analysis

    Neuronal and glial cell death caused by axonal injury sometimes contributes to whole brain pathology after traumatic brain injury (TBI). We show that neuroprotection by 2 types of immunosuppressants, cyclospor...

    Y. Ishikawa, H. Uchino, S. Morota, C. Li, T. Takahashi, Y. Ikeda… in Brain Edema XIII (2006)

  2. No Access

    Chapter and Conference Paper

    A novel neuroprotective compound FR901459 with dual inhibition of calcineurin and cyclophilins

    Brain ischemia leads to severe damage in the form of delayed neuronal cell death. In our study, we show that the marked neuroprotection of the new immunosuppressant FR901495 in forebrain ischemia is due not on...

    H. Uchino, S. Morota, T. Takahashi, Y. Ikeda, Y. Kudo, N. Ishii… in Brain Edema XIII (2006)

  3. No Access

    Chapter and Conference Paper

    Mitochondrial Dysfunction and Maturation of Brain Damage After Transient Ischemia

    The damage incurred by neurons and glial cells after ischemia and reperfusion is caused by events occurring during three periods: the period of ischemia, the maturation period, and the sequence of events leadi...

    B. K. Siesjö, H. Uchino, T. Yoshimoto… in Maturation Phenomenon in Cerebral Ischemia… (2001)

  4. No Access

    Chapter and Conference Paper

    Role and Mechanisms of Secondary Mitochondrial Failure

    Ischemia is accompanied by mitochondrial dysfunction, as assessed by measurements of mitochondrial respiratory activities in vitro. Following brief periods of ischemia, mitochondrial function is usually normalize...

    Bo K. Siesjö M.D., Ph.D., E. Elmér… in Current Progress in the Understanding of S… (1999)

  5. No Access

    Chapter and Conference Paper

    Role of Mitochondria in Immediate and Delayed Reperfusion Damage

    Ischemia leads to mitochondrial dysfunction. This is reversible if ischemia is of brief duration, but secondary mitochondrial damage is observed after longer periods of ischemia, particularly in selectively vu...

    B. K. Siesjö, Y. Ouyang, T. Kristián… in Maturation Phenomenon in Cerebral Ischemia… (1999)

  6. No Access

    Article

    Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects

     A recent study from this laboratory has shown that brief transient ischemia (2 min 30 s) in normo- and hyperglycemic rats leads to moderate neuronal necrosis in CA1 cells of the hippocampus, of equal density ...

    J. Folbergrová, **-An Li, H. Uchino, Maj-Lis Smith… in Experimental Brain Research (1997)

  7. No Access

    Article

    The neuronal organization of horizontal semicircular canalactivated inhibitory vestibulocollic neurons in the cat

    1.The somatic location and axonal projections of inhibitory vestibular nucleus neurons activated by the horizontal semicircular canal nerve (HCN) were studied in anesthetized cats. Cats were anesthetized with ...

    N. Isu, A. Sakuma, K. Hiranuma, H. Uchino, S -I. Sasaki… in Experimental Brain Research (1991)