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  1. Article

    Open Access

    Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma

    Chemotherapy for primary central nervous system lymphoma (PCNSL) is based on methotrexate (MTX), which interferes with both nucleic acid synthesis and methionine metabolism. We have reported previously that ge...

    M Linnebank, S Moskau, A Kowoll, A Semmler, C Bangard… in British Journal of Cancer (2012)

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  2. No Access

    Article

    FDG-PET in immunocompetent patients with primary central nervous system lymphoma: correlation with MRI and clinical follow-up

    The role of FDG-PET in primary central nervous system lymphoma (PCNSL) is unclear. It was the aim of this study to investigate the role of FDG-PET in detecting PCNSL and in predicting response to chemotherapy.

    H. Palmedo, H. Urbach, H. Bender… in European Journal of Nuclear Medicine and M… (2006)

  3. Article

    Open Access

    The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma

    Primary central nervous system lymphomas (PCNSL) frequently reveal genomic instability. We analysed different functional genetic variants affecting the folate and homocysteine metabolism important for DNA inte...

    M Linnebank, S Schmidt, H Kölsch, A Linnebank, R Heun… in British Journal of Cancer (2004)

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  4. No Access

    Article

    Intraventricular and Intravenous Treatment of a Patient with Refractory Primary CNS Lymphoma using Rituximab

    The treatment of primary central nervous system lymphoma (PCNSL) with chemo- and radiotherapy is efficient in terms of tumor response. However, time to tumor progression often is of short duration and leptomen...

    H. Pels, H. Schulz, O. Manzke, E. Hom, A. Thall, A. Engert in Journal of Neuro-Oncology (2002)

  5. No Access

    Article

    A novel type of metastatically spreading subcutaneous aspergillosis without epidermal lesions following allogeneic stem cell transplantation

    Systemic mycosis is among the most feared opportunistic infections in the immunocompromised host. Difficulty and delay in diagnosis and treatment often result in poor outcomes. In this communication a metastat...

    OA Cornely, H Pels, U Bethe, M Seibold, K Toepelt… in Bone Marrow Transplantation (2001)

  6. No Access

    Article

    Primary central nervous system immunocytoma: MRI and spectroscopy

    We report on a young woman with a primary cerebral immunocytoma. Most primary cerebral nervous system lymphomas (PCNSL) are highly malignant undifferentiated B-cell tumours, there are few data on the clinical...

    E. Braks, H. Urbach, H. Pels, F. Träber, W. Block, H. H. Schild in Neuroradiology (2000)

  7. No Access

    Article

    Neurologic Sequelae of Treatment of Primary CNS Lymphomas

    Novel efficient and aggressive treatment protocols for primary CNS lymphomas have resulted in an increasing number of long term survivors. Follow up data show that in a substantial fraction of these patients, ...

    U. Schlegel, H. Pels, R. Oehring, I. Blümcke in Journal of Neuro-Oncology (1999)