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  1. Article

    Open Access

    Genome-wide functions of PML–RARα in acute promyelocytic leukaemia

    PML—RAR (retinoic acid receptor)α is the hallmark protein of acute promyelocytic leukaemia, a highly malignant subtype of acute myeloid leukaemia that accounts for approximately 10% of all AML cases. Recently, se...

    S Saeed, C Logie, H G Stunnenberg, J H A Martens in British Journal of Cancer (2011)

  2. No Access

    Chapter

    Strategies for Epigenome Analysis

    The eukaryotic genome is packaged into nucleosomes, which form the basal unit of chromatin, the physiological form of DNA within the nucleus. Apart from its function in compacting the immense nuclear DNA molec...

    A.B. Brinkman, H.G. Stunnenberg in Epigenomics (2009)