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    Protocol

    A Systems Toxicology Approach to Investigating the Cardiovascular Effects of Cigarette Smoke and Environmental Pollutants in ApoE-Deficient Mice

    Epidemiological evidence indicates that exposure to combustion-derived particles is linked to an increased risk of cardiovascular disease. Despite this strong association, there remains a lack of data that can...

    Héctor De León, Stephanie Boue, Manuel C. Peitsch in Computational Systems Toxicology (2015)

  2. Article

    Open Access

    A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability

    Numerous inflammation-related pathways have been shown to play important roles in atherogenesis. Rapid and efficient assessment of the relative influence of each of those pathways is a challenge in the era of ...

    Héctor De León, Stéphanie Boué, Walter K Schlage in Journal of Translational Medicine (2014)