6 Result(s)

Article

Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage

Healthcare system data (HSD) are increasingly used in clinical trials, augmenting or replacing traditional methods of collecting outcome data. This study, PRIMORANT, set out to identify, in the UK context, iss...

Alice-Maria Toader, Marion K. Campbell, Jennifer K. Quint, Michael Robling… in Trials (2024)

Article

Exploring flexible polynomial regression as a method to align routine clinical outcomes with daily data capture through remote technologies

Clinical outcomes are normally captured less frequently than data from remote technologies, leaving a disparity in volumes of data from these different sources. To align these data, flexible polynomial regress...

Nicole Filipow, Eleanor Main, Gizem Tanriver… in BMC Medical Research Methodology (2023)

Article

A DELPHI study priority setting the remaining challenges for the use of routinely collected data in trials: COMORANT-UK

Researchers are increasingly seeking to use routinely collected data to support clinical trials. This approach has the potential to transform the way clinical trials are conducted in the future. The availabili...

Adam D. N. Williams, Gwyneth Davies, Amanda J. Farrin, Marion Mafham… in Trials (2023)

Article

Future therapies for cystic fibrosis

We are currently witnessing transformative change for people with cystic fibrosis with the introduction of small molecule, mutation-specific drugs capable of restoring function of the defective protein, cystic...

Lucy Allen, Lorna Allen, Siobhan B. Carr, Gwyneth Davies… in Nature Communications (2023)

Article

Editorial

Gwyneth Davies, Paul Aurora, Archana Patel, Yamini Pusdekar in Indian Pediatrics (2019)