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Article
Open AccessAnalysis of the association between salivary proteins and oral mucositis in patients with head and neck cancer undergoing IMRT: a longitudinal study
This longitudinal study assessed the association between salivary protein composition and the clinical onset/severity of oral mucositis (OM) in patients with head and neck tumours treated with intensity-modula...
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Article
Open AccessNovel bacterial proteolytic and metabolic activity associated with dental erosion-induced oral dysbiosis
Dental erosion is a disease of the oral cavity where acids cause a loss of tooth enamel and is defined as having no bacterial involvement. The tooth surface is protected from acid attack by salivary proteins t...
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Article
Open AccessSalivary peptidome analysis and protease prediction during orthodontic treatment with fixed appliances
Orthodontic tooth movement (OTM) occurs through proteolytic remodelling within the periodontium following the application of external force to the tooth. This study describes the first characterization of the ...
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Article
Open AccessMolecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation
Escherichia coli is a Gram-negative bacterium that colonises the human intestine and virulent strains can cause severe diarrhoeal and extraintestinal diseases. The protein SslE is secreted by a range of pathogeni...
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Article
Open AccessAnatomical stability of human fungiform papillae and relationship with oral perception measured by salivary response and intensity rating
Fungiform papillae house taste buds on the anterior dorsal tongue. Literature is inconclusive as to whether taste perception correlates with fungiform papillae density (FPD). Gustatory reflexes modulate the am...
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Saliva and Gingival Crevicular Fluid: Contributions to Mucosal Defense
In this chapter the authors describe the main components of saliva and gingival crevicular fluid and how they may be useful for diagnostic purposes. Specifically, we looked at periodontal disease, orthodontic ...
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Article
Open AccessSelection of housekee** genes for gene expression studies in the adult rat submandibular gland under normal, inflamed, atrophic and regenerative states
Real-time PCR is a reliable tool with which to measure mRNA transcripts, and provides valuable information on gene expression profiles. Endogenous controls such as housekee** genes are used to normalise mRNA...
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Article
Early markers of regeneration following ductal ligation in rat submandibular gland
Rat submandibular glands can recover their function and secretory protein content following ductal ligation-induced atrophy. Morphological studies have established that following ligation, deligation of the gl...
