5 Result(s)
within
Guozhong Zhang
Biomedicine
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Article
Open AccessMutagenesis of the di-leucine motif in the cytoplasmic tail of newcastle disease virus fusion protein modulates the viral fusion ability and pathogenesis
Newcastle disease virus (NDV) is a highly infectious viral disease, which can affect chickens and many other kinds of birds. The main virulence factor of NDV, the fusion (F) protein, is located on the viral en...
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Article
A study on the infection status and transmission of avian leukosis virus subgroup J in Hy-line brown roosters
Avian leukosis virus subgroup J (ALV-J) is the most prevalent subgroup in chickens and exhibits increased pathogenicity and stronger horizontal and vertical transmission ability among different breeds. Althoug...
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Article
NP protein and F protein of pigeon paramyxovirus type 1 are associated with its low pathogenicity in chickens
In this study, we investigated which structural proteins of pigeon paramyxovirus type 1 (PPMV-1) are responsible for its low pathogenicity in chickens. The results revealed that the pathogenicity of the virus ...
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Article
Open AccessEfficacy of an inactivated bivalent vaccine against the prevalent strains of Newcastle disease and H9N2 avian influenza
Newcastle disease (ND) and avian influenza subtype H9N2 (H9N2 AI) are two of the most important diseases of poultry, causing severe economic losses in the global poultry industry. Vaccination is an effective w...
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Article
Genomic characterization of two avian paramyxovirus type 2 isolates from chickens in China
The complete genome sequences were determined for avian paramyxovirus type 2 (APMV-2) strains F8 and NK isolated from chickens in China. Both strains had a genome of 14,904 nucleotides (nt) in length, which fo...
