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  1. No Access

    Article

    Protective effect of Platycodon grandiflorus polysaccharide on apoptosis and mitochondrial damage induced by pseudorabies virus in PK-15 cells

    Previous studies have confirmed that Platycodon grandiflorus polysaccharide (PGPSt) has the effects of regulating immunity and anti-apoptosis, but its effect on mitochondrial damage and apoptosis caused by PRV in...

    Yuxiao **ng, Yukun Cui, Guanlong Xu, Changxi Qi in Cell Biochemistry and Biophysics (2023)

  2. Article

    Open Access

    Permafrost degradation increases risk and large future costs of infrastructure on the Third Pole

    The damage to infrastructure caused by near-surface permafrost degradation is directly related to the well-being of 10 million people and the sustainable development on the Qinghai-Tibet Plateau, the Third Pol...

    Youhua Ran, Guodong Cheng, Yuanhong Dong, Jan Hjort in Communications Earth & Environment (2022)

  3. No Access

    Article

    Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells

    Related studies have shown that chromium (Cr) is toxic to cells, and hydrogen can protect cells by regulating endoplasmic reticulum (ER) stress and autophagy. However, there are few reports on the protective e...

    Kang** Liu, Yukun Cui, Hongyan Li, Changxi Qi in Biological Trace Element Research (2022)

  4. No Access

    Article

    Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium

    As a highly toxic heavy metal, chromium has caused a certain threat to public health and livestock breeding in recent years. In poultry, as one of our most commonly consumed meat product, its health issues wil...

    Yue Wang, Lumei Wang, **aozhou Wang, Guodong Cheng in Biological Trace Element Research (2022)

  5. No Access

    Article

    Platycodon grandiflorus Polysaccharide with Anti-Apoptosis, Anti-Oxidant and Anti-Inflammatory Activity Against LPS/D-GalN Induced Acute Liver Injury in Mice

    This study aimed to explore the mechanism of hepatoprotective effect of Platycodon grandiflorus polysaccharides (PGPSt) on LPS/D-galactose (D-GalN)-induced acute liver injury in mice. The pathological changes of ...

    Changxi Qi, Li** Li, Guodong Cheng, Bin **ao in Journal of Polymers and the Environment (2021)

  6. No Access

    Article

    Down-regulation of PTTG1 suppresses PDGF-BB-induced proliferation, migration and extracellular matrix production of airway smooth muscle cells (ASMCs) by regulating PI3K/AKT/mTOR signaling pathway

    To investigate the biological functions and the molecular mechanisms of PTTG1 in PDGF-BB-induced ASMCs.

    Guodong Cheng, **aowei Liu, ** Li, Yan Li in Molecular & Cellular Toxicology (2021)

  7. No Access

    Article

    Inflammatory injury and mitophagy of the brain in chicken exposed to Cr(VI)

    The aim of this study is to determine whether Cr(VI) can induce inflammatory injury in chicken brain and influence mitophagy and related mechanisms. A total of 120 hyline brown chickens (1 day old, 20±3g) were...

    Shuhua Guo, **aozhou Wang, Lumei Wang in Environmental Science and Pollution Resear… (2021)

  8. No Access

    Article

    Boosting geoscience data sharing in China

    Enabling public sharing of scientific data in China not only needs top-down mandates but also incentive mechanisms that boost confidence and willingness to engage in data-sharing practices among Chinese resear...

    **n Li, Guodong Cheng, Liangxu Wang, Juanle Wang, Youhua Ran, Tao Che in Nature Geoscience (2021)

  9. No Access

    Article

    Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI)

    Cr(VI) is a heavy metal environmental pollutant and carcinogen. Excessive Cr(VI) exposure injures kidneys. This study aimed to investigate mitophagy induced by mitochondrial function damage in chicken kidney e...

    Yue Wang, **aozhou Wang, Lumei Wang, Guodong Cheng in Biological Trace Element Research (2021)

  10. No Access

    Article

    Map** the permafrost stability on the Tibetan Plateau for 2005–2015

    Data scarcity is a major obstacle for high-resolution map** of permafrost on the Tibetan Plateau (TP). This study produces a new permafrost stability distribution map for the 2010s (2005–2015) derived from t...

    Youhua Ran, **n Li, Guodong Cheng, Zhuotong Nan in Science China Earth Sciences (2021)

  11. No Access

    Chapter and Conference Paper

    Experimental Study on Pore Water Pressure and Microstructures of Silty Clay Under Freeze-Thaw Cycles

    The variations on physical properties and microstructures of soils are essential to explore the freeze-thaw mechanisms. We do some experiments on freeze-thaw test of Qinghai-Tibet silty clay and cryo-scanning ...

    Dan Wang, Chengsong Yang, Guodong Cheng in Transportation Soil Engineering in Cold Re… (2020)

  12. Article

    Open Access

    No trends in spring and autumn phenology during the global warming hiatus

    Phenology plays a fundamental role in regulating photosynthesis, evapotranspiration, and surface energy fluxes and is sensitive to climate change. The global mean surface air temperature data indicate a global...

    Xufeng Wang, **gfeng **ao, **n Li, Guodong Cheng, Mingguo Ma in Nature Communications (2019)

  13. No Access

    Reference Work Entry In depth

    Field Experimental Design for a Watershed Observing System

    A watershed, regarded as the ideal unit for practicing earth system science, possesses all of the complexities of the land surface system. Thus, building a watershed observing system and conducting a field exp...

    **n Li, Guodong Cheng, Chunfeng Ma in Observation and Measurement of Ecohydrolog… (2019)

  14. No Access

    Living Reference Work Entry In depth

    Field Experimental Design for Watershed Observing System

    A watershed, regarded as the ideal unit for practicing earth system science, possesses all of the complexities of the land surface system. Thus, building a watershed observing system and conducting a field exp...

    **n Li, Guodong Cheng, Chunfeng Ma in Observation and Measurement of Ecohydrolog…

  15. No Access

    Article

    An improved model for soil surface temperature from air temperature in permafrost regions of Qinghai-**zang (Tibet) Plateau of China

    Soil temperature plays a key role in hydro-thermal processes in environments and is a critical variable linking surface structure to soil processes. There is a need for more accurate temperature simulation mod...

    Guojie Hu, **aodong Wu, Lin Zhao, Ren Li, Tonghua Wu in Meteorology and Atmospheric Physics (2017)

  16. No Access

    Article

    Spatio-temporal analysis and simulation on shallow rainfall-induced landslides in China using landslide susceptibility dynamics and rainfall I-D thresholds

    An empirical simulation method to simulate the possible position of shallow rainfall-induced landslides in China has been developed. This study shows that such a simulation may be operated in real-time to high...

    WeiYue Li, Chun Liu, Marco Scaioni, WeiWei Sun, Yu Chen in Science China Earth Sciences (2017)

  17. No Access

    Article

    Human activity impacts on the stem radial growth of Populus euphratica riparian forests in China’s E**a Oasis, using tree-ring analysis

    The heterogeneous stem radial growth of Populus euphratica and its correlation with hydrology and climate factors were investigated by a tr...

    **aomei Peng, Shengchun **ao, Guodong Cheng, Honglang **ao, Quanyan Tian in Trees (2017)

  18. No Access

    Article

    A comparison of two photosynthesis parameterization schemes for an alpine meadow site on the Qinghai-Tibetan Plateau

    Photosynthesis is a very important sub-process in the carbon cycle and is a crucial sub-modular function in carbon cycle models. In this study, two typical photosynthesis parameterization schemes were compared...

    Xufeng Wang, Guodong Cheng, **n Li, Ling Lu in Theoretical and Applied Climatology (2016)

  19. Article

    Open Access

    A naturally-occurring ‘cold earth’ spot in Northern China

    Permafrost is determined to a large extent by the Earth’s surface temperature, therefore it distributes mainly in high altitude and latitude regions. However, stable, warm (about −1 °C) permafrost occurs withi...

    Fujun Niu, Guodong Cheng, Yonghong Niu, Mingyi Zhang, **g Luo in Scientific Reports (2016)

  20. No Access

    Article

    An analytical model for estimating soil temperature profiles on the Qinghai-Tibet Plateau of China

    Soil temperature is a key variable in the control of underground hydro-thermal processes. To estimate soil temperature more accurately, this study proposed a solution method of the heat conduction equation of ...

    Guojie Hu, Lin Zhao, **aodong Wu, Ren Li, Tonghua Wu, in Journal of Arid Land (2016)

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