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  1. Article

    Open Access

    Expression alteration of serum exosomal circular RNAs in obstructive sleep apnea patients with acute myocardial infarction

    Circular RNAs (circRNAs) are recently identified as a class of non-coding RNAs that participate in the incidence of acute myocardial infarction (AMI). However, circRNAs expression pattern in obstructive sleep ...

    Jie-feng Huang, Ning-Fang Lian, Guo-Fu Lin, Han-Sheng **e in BMC Medical Genomics (2023)

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    Article

    Effect of chronic intermittent hypoxia on gene expression profiles of rat liver: a better understanding of OSA-related liver disease

    Obstructive sleep apnea (OSA) and OSA-associated chronic intermittent hypoxia (CIH) have been suggested to be associated with increased risk of liver disease. Little is known about the biological pathophysiolo...

    Li-Da Chen, Qin Chen, Xue-Jun Lin, Qing-Shi Chen, Yu-Zhen Huang in Sleep and Breathing (2020)

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    Article

    MicroRNA-195 regulates steroid receptor coactivator-3 protein expression in hepatocellular carcinoma cells

    Multiple studies have shown that steroid receptor coactivator-3 (SRC-3) is upregulated and promotes cell proliferation in several human cancers, including breast, lung, and prostate carcinoma. However, its mol...

    Hong-Lei Jiang, Hao Yu, Xu Ma, Dong Xu, Guo-Fu Lin, Dong-Yan Ma in Tumor Biology (2014)

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    Article

    Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Met-deficient hepatocellular carcinoma in vivo

    PHA665752 (PHA), a selective small molecule c-Met Inhibitor, potently inhibited HGF-stimulated and constitutive c-Met phosphorylation, as well as HGF and c-Met-driven phenotypes of a variety of tumor cells inc...

    Hong-Lei Jiang, Jun-Zhe **, Dan Wu, Dong Xu, Guo-Fu Lin in Molecular Biology Reports (2013)