3,073 Result(s)

Article

Nonlinear spatiotemporal characteristics of wind–rain flow around the trains passing through the tunnel entrance during rainstorms

Tropical storms present a significant risk to the safety of high-speed trains due to the extreme wind and rainfall they bring. This study employs Eulerian multiphase and Shear-Stress Transport k-ω turbulence mode...

Guo-Zhi Li, E Deng, Yi-Qing Ni, De-Hui Ouyang, Wei-Chao Yang in Nonlinear Dynamics (2024)

Article

Retraction Note: LncRNA LINC00337 sponges mir-1285-3p to promote proliferation and metastasis of lung adenocarcinoma cells by upregulating YTHDF1

Ru-nan Zhang, Dong-mei Wu, Li-** Wu, Guo-wei Gao in Cancer Cell International (2024)

Article

Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma

Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...

Bao-Ye Sun, Dai Zhang, Wei Gan, **g-Fang Wu… in Journal of Cancer Research and Clinical On… (2024)

Article

Correction to: Process Optimization and Influencing Factors of Supersonic High-Energy Plasma Spraying of Al₂O₃-PF Composite Coatings on Polymer Matrix Composite Surface

Ming Liu, Qi-qing Peng, Yan-fei Huang, Guo-zheng Ma… in Journal of Thermal Spray Technology (2024)

Article

Correction: lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus

Hai-Ting Liu, Yong-**n Zou, Wen-jie Zhu, Sen-Liu… in Cell Death & Differentiation (2024)

Article

Analyzing the correlation between low proportion of hobnail features in papillary thyroid carcinoma and clinical aggressiveness risk

Hobnail features may enhance the clinical aggressiveness of papillary thyroid carcinoma (PTC). However, whether a low proportion (<30%) of these features contributes to increased PTC aggressiveness remains unc...

Wen-Shun Liu, Yan-Ting Duan, Guo-Qing Ru, Wan-Yuan Chen, Yuan Chen, Tian Lv… in Endocrine (2024)

Article

Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a

Quiescence, a hallmark of adult neural stem cells (NSCs), is required for maintaining the NSC pool to support life-long continuous neurogenesis in the adult dentate gyrus (DG). Whether long-lasting epigenetic ...

Ting Zhao, Yan Hong, Bowen Yan, Suming Huang, Guo-li Ming… in Nature Communications (2024)

Article

Easily misdiagnosed X-linked adrenoleukodystrophy

Addison’s disease and X-linked adrenoleukodystrophy (X-ALD) (Addison’s-only) are two diseases that need to be identified. Addison’s disease is easy to diagnose clinically when only skin and mucosal pigmentatio...

Qiu-Hong Wang, Yang-Yang Wang, **g Wang, Li-Ying Liu… in Italian Journal of Pediatrics (2024)

Article

The Garden of Forking Paths: Reinterpreting Haseman-Elston Regression for a Genotype-by-Environment Model

Haseman-Elston regression (HE-reg) has been known as a classic tool for detecting an additive genetic variance component. However, in this study we find that HE-reg can capture GxE under certain conditions, so...

Guo-Bo Chen in Behavior Genetics (2024)

Article

Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury

Reperfusion therapy is critical for saving heart muscle after myocardial infarction, but the process of restoring blood flow can itself exacerbate injury to the myocardium. This phenomenon is known as myocardi...

Wan-ting Meng, **g Zhu, Ya-chao Wang, Chang-le Shao… in Journal of Nanobiotechnology (2024)

Article

Tagging large CNV blocks in wheat boosts digitalization of germplasm resources by ultra-low-coverage sequencing

The massive structural variations and frequent introgression highly contribute to the genetic diversity of wheat, while the huge and complex genome of polyploid wheat hinders efficient genoty** of abundant v...

Jianxia Niu, Wenxi Wang, Zihao Wang, Zhe Chen, **aoyu Zhang, Zhen Qin… in Genome Biology (2024)

Article

Different effects of inspiratory duration and expiratory duration on heart rate deceleration capacity and heart rate asymmetry

Low values of heart rate deceleration capacity (DC) and heart rate asymmetry (HRA) are associated with cardiovascular risks. Slow respiration has been proven to enhance the magnitudes of these indexes, but ind...

Yong-** Wang, Terry B. J. Kuo, Guo-Zhi Wang… in European Journal of Applied Physiology (2024)

Article

Direct radical functionalization of native sugars

Naturally occurring (native) sugars and carbohydrates contain numerous hydroxyl groups of similar reactivity^1,2. Chemists, therefore, rely typically on laborious, multi-step protecting-group strategies³ to conver...

Yi Jiang, Yi Wei, Qian-Yi Zhou, Guo-Quan Sun, **a-** Fu, Nikita Levin… in Nature (2024)

Article

Improvement in corrosion resistance of Mg₉₇Zn₁Y₂ alloy by Zr addition

Magnesium alloys, known for their exceptional lightweight properties, have presented challenges in various applications due to their limited corrosion resistance. In this study, the corrosion resistance of Mg₉₇Zn

Di-qing Wan, Yu-meng Sun, Yan-dan Xue, Shao-yun Dong, Guo-liang Han… in China Foundry (2024)

Article

A pan-KRAS degrader for the treatment of KRAS-mutant cancers

KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms of KRAS play a crucial role in driving cancer progression and conferring resistance to treatment. While there have bee...

Jie Yang, Qiao-Li Wang, Guan-Nan Wang, Jia-Cong Ye, Zi-Qian Li… in Cell Discovery (2024)

Article

Analysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy

Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...

Hong Chen, Ji-Hong Zhang, Qin Hao… in International Journal of Colorectal Disease (2024)

Article

Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma

Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma (ICC). However, it remains elusive how ICC cells subvert immu...

Bao-Ye Sun, Zhu-Tao Wang, Ke-Zhu Chen, Yang Song, **g-Fang Wu… in Cell Death Discovery (2024)

Article

Localized, highly efficient secretion of signaling proteins by migrasomes

Migrasomes, enriched with signaling molecules such as chemokines, cytokines and angiogenic factors, play a pivotal role in the spatially defined delivery of these molecules, influencing critical physiological ...

Haifeng Jiao, **aopeng Li, Ying Li, Yuting Guo, **aoyu Hu, Takami Sho… in Cell Research (2024)

Article

Enhancing hepatocellular carcinoma management: prognostic value of integrated CCL17, CCR4, CD73, and HHLA2 expression analysis

Hepatocellular carcinoma (HCC) is a critical global health concern, with existing treatments benefiting only a minority of patients. Recent findings implicate the chemokine ligand 17 (CCL17) and its receptor C...

Wei Gan, Bao-Ye Sun, Zhang-Fu Yang, Cheng Ye… in Journal of Cancer Research and Clinical On… (2024)

Article

The effect of hyperlipidemia on overall survival in patients with cancer was differentiated by BMI and hyperlipidemia type

The impact of lipids on the overall survival (OS) of patients with malignancy has not yet been clarified. This study aimed to evaluate the effect of hyperlipidemia on the OS among Chinese patients based on Bod...

Hai-Ying Tian, Ming Yang, Hai-Lun **e, Guo-Tian Ruan, Yi-Zhong Ge… in Nutrition & Metabolism (2024)