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Article
Laser interstitial thermal therapy in the treatment of brain metastases: the relationship between changes in postoperative magnetic resonance imaging characteristics and tumor recurrence
Laser interstitial thermal therapy (LITT) has been used to treat brain metastases (BMs) in several countries, and its safety and effectiveness have been confirmed. In most cases, magnetic resonance imaging (MR...
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Article
Open AccessIdentification and gene expression profiling of human gonadotrophic pituitary adenoma stem cells
Gonadotrophic pituitary adenoma is a major subtype of pituitary adenoma in the sellar region, but it is rarely involved in the hypersecretion of hormones into blood; thus, it is commonly regarded as “non-funct...
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Article
A Novel Imaging Grading Biomarker for Predicting Hearing Loss in Acoustic Neuromas
The aim of this study was to investigate an imaging biomarker based on contrast enhanced T1-weighted and T2-weighted magnetic resonance imaging (MRI) to determine the hearing loss related to acoustic neuromas ...
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Article
Comprehensive analysis of the immunological landscape of pituitary adenomas: implications of immunotherapy for pituitary adenomas
Immunotherapies for solid tumor are gaining traction in the clinic, however, the immunological landscape of pituitary adenomas (PAs) is not well defined. In the present study, we used the RNA-seq data of PAs t...
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Article
Mixed gangliocytoma-pituitary adenoma in the sellar region: a large-scale single-center experience
Mixed gangliocytoma-pituitary adenoma is an extremely rare tumor occurring in the sellar region, histologically composed of both gangliocytic and pituitary adenomatous architectures. The histogenesis of these ...
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Article
Evidence of dysexecutive syndrome in patients with acromegaly
This study aimed to explore different aspects of executive function in patients with acromegaly and investigate the cause of dysexecutive syndrome in these patients.
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Article
Open AccessAn atypical pituitary adenoma with a high degree of malignancy: a case report
Pituitary carcinoma is very rare and hard to diagnose. However, some atypical pituitary adenomas present with a high rate of proliferation and extensive invasion, suggesting a tumor with a high degree of malig...
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Article
Effect comparisons among treatment measures on progression-free survival in patients with skull base chordomas: a retrospective study of 234 post-surgical cases
Skull base chordoma (SBC) is a rare and refractory tumor with a high rate of relapse. We aimed to investigate the relationships between different treatment measures and progression-free survival (PFS) outcomes.
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Article
Microsurgical management of primary jugular foramen meningiomas: a series of 22 cases and review of the literature
This study summarized clinical manifestations, surgical management, histological grading, and long-term outcome of jugular foramen meningiomas (JFMs). Retrospective study was performed in 22 consecutive patien...
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Article
Open AccessNeurosurgical publications in China: an analysis of the web of science database
Neurosurgery in China has made great progress. The aim of this study was to analyze neurosurgical publications by Chinese authors using the Web of Science database as a way to illustrate the current state of n...
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Article
Open AccessDifferential expression of p42.3 in low- and high-grade gliomas
Malignant gliomas are the most common form of primary malignant brain tumor. It has recently been suggested that genetic changes are involved in the progression of malignant gliomas. In previous studies, a nov...
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Article
Using the C7-T3 spinous processes as landmarks for the localization of thoracic spinal lesions: technique notes
The authors describe a method of using the C7-T3 spinous processes visualized on MRI as landmarks for localizing thoracic spinal lesions in 19 cases. This method included six steps. First, the “spinous process...
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Article
Open AccessSurgical resection of large and giant petroclival meningiomas via a modified anterior transpetrous approach
The authors describe a modified anterior transpetrous approach (ATPA) for the surgical resection of 21 cases of petroclival meningiomas (PCMs). Briefly, a curved periauricular skin incision was used. The cereb...
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Article
Expression of pituitary tumor transforming gene (PTTG) in human pituitary macroadenomas
The purpose of this study was to elucidate the relationship between pituitary tumor transforming gene (PTTG) and invasiveness in pituitary macroadenomas and to determine the association between PTTG and both t...
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Article
Prognostic factors for long-term outcome of patients with surgical resection of skull base chordomas—106 cases review in one institution
Skull base chordoma are still challenging. Between May 1993 and June 2005, 106 consecutive patients with skull base chordoma underwent surgical removal at Skull Base Division of Neurosurgery, Bei**g Tiantan H...
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Article
Two-bone flap craniotomy for the transpetrosal–presigmoid approach to avoid a bony defect in the periauricular area after surgery on petroclival lesions: technical note
The authors describe a two-bone-flap craniotomy technique to avoid the bone defect caused by the transpetrosal–presigmoid approach. Briefly, this technique includes three steps. The first step is to elevate a ...