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    Article

    Tight junction protein claudin-2 promotes cell entry of Bombyx mori cypovirus

    Claudin-2 is a major component of tight junctions (TJs), which play an important role in reovirus entry into host cells. The Bombyx mori cytoplasmic polyhedosis virus (BmCPV) relates to the cypovirus strain of th...

    Min Zhu, **ng Zhang, Jun Pan, Hanxue Zhu in Applied Microbiology and Biotechnology (2021)

  2. Article

    Open Access

    Functional characterization of BmOVOs in silkworm, Bombyx mori

    In our previous study, we identified four isoforms of the Bmovo gene, Bmovo-1, Bmovo-2, Bmovo-3 and Bmovo-4 from the silkworm ovary and verified that ovarian development was regulated by the BmOVO proteins. Resul...

    Min Zhu, **aolong Hu, Zi Liang, Mengsheng Jiang, Renyu Xue, Yongchang Gong in BMC Genomics (2019)

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    Article

    Functions and impact of tal-like genes in animals with regard to applied aspects

    A large number of DNAs in eukaryote genomes can code for atypical transcripts, and their functions are controversial. It has been reported that the transcripts contain many small open reading frames (sORFs), w...

    Min Zhu, **aolong Hu, Guangli Cao, Renyu Xue in Applied Microbiology and Biotechnology (2018)

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    Article

    Identification of tarsal-less peptides from the silkworm Bombyx mori

    The polycistronic and non-canonical gene tarsal-less (tal, known as pri) was reported to be required for embryonic and imaginal development in Drosophila; however, there are few reports of the tal gene in the sil...

    Guangli Cao, Yongchang Gong, **aolong Hu, Min Zhu in Applied Microbiology and Biotechnology (2018)

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    Article

    Exogenous gene can be expressed by a recombinant Bombyx mori cypovirus

    Bombyx mori cypovirus (BmCPV) is one of the major viral pathogen for silkworm, and the genome of BmCPV is composed of 10 dsRNA segments. As construction system of recombinant BmCPV (rBmCPV) is sc...

    Rui Guo, Guangli Cao, Renyu Xue, Dhiraj Kumar in Applied Microbiology and Biotechnology (2018)

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    Article

    Integrin beta and receptor for activated protein kinase C are involved in the cell entry of Bombyx mori cypovirus

    Receptor-mediated endocytosis using a β1 integrin-dependent internalization was considered as the primary mechanism for the initiation of mammalian reovirus infection. Bombyx mori cypovirus (BmCPV) is a member of...

    Yiling Zhang, Guangli Cao, Liyuan Zhu, Fei Chen in Applied Microbiology and Biotechnology (2017)

  7. No Access

    Article

    Proteomic analysis of BmN cell lipid rafts reveals roles in Bombyx mori nucleopolyhedrovirus infection

    The mechanism of how Bombyx mori nucleopolyhedrovirus (BmNPV) enters cells is unknown. The primary components of membrane lipid rafts are proteins and cholesterol, and membrane lipid rafts are thought to be an ac...

    **aolong Hu, Min Zhu, Zi Liang, Dhiraj Kumar, Fei Chen in Molecular Genetics and Genomics (2017)

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    Article

    Transcriptome analysis of BmN cells following over-expression of BmSTAT

    The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway are involved in immune response, cell proliferation, differentiation, cell migration and apoptosis. In order to ...

    **aolong Hu, ** Zhang, Jian Wang, Moli Huang, Renyu Xue in Molecular Genetics and Genomics (2015)

  9. No Access

    Article

    The gene expression profile of resistant and susceptible Bombyx mori strains reveals cypovirus-associated variations in host gene transcript levels

    High-throughput paired-end RNA sequencing (RNA-Seq) was performed to investigate the gene expression profile of a susceptible Bombyx mori strain, Lan5, and a resistant B. mori strain, Ou17, which were both orally...

    Rui Guo, Simei Wang, Renyu Xue, Guangli Cao in Applied Microbiology and Biotechnology (2015)