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  1. Article

    Open Access

    Decoding the RNA viromes in rodent lungs provides new insight into the origin and evolutionary patterns of rodent-borne pathogens in Mainland Southeast Asia

    As the largest group of mammalian species, which are also widely distributed all over the world, rodents are the natural reservoirs for many diverse zoonotic viruses. A comprehensive understanding of the core ...

    Zhiqiang Wu, Yelin Han, Bo Liu, Hongying Li, Guangjian Zhu, Alice Latinne in Microbiome (2021)

  2. Article

    Open Access

    Origin and cross-species transmission of bat coronaviruses in China

    Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of COVID-19. However, the evolution and di...

    Alice Latinne, Ben Hu, Kevin J. Olival, Guangjian Zhu in Nature Communications (2020)

  3. Article

    Open Access

    Fabrication of High-Quality and Strain-Relaxed GeSn Microdisks by Integrating Selective Epitaxial Growth and Selective Wet Etching Methods

    GeSn is a promising material for the fabrication of on-chip photonic and nanoelectronic devices. Processing techniques dedicated to GeSn have thus been developed, including epitaxy, annealing, ion implantation...

    Guangjian Zhu, Tao Liu, Zhenyang Zhong, **nju Yang in Nanoscale Research Letters (2020)

  4. Article

    Open Access

    Comparative analysis of rodent and small mammal viromes to better understand the wildlife origin of emerging infectious diseases

    Rodents represent around 43% of all mammalian species, are widely distributed, and are the natural reservoirs of a diverse group of zoonotic viruses, including hantaviruses, Lassa viruses, and tick-borne encep...

    Zhiqiang Wu, Liang Lu, Jiang Du, Li Yang, **anwen Ren, Bo Liu, **yong Jiang in Microbiome (2018)

  5. Article

    Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China

    Ning Wang, Shi-Yue Li, **ng-Lou Yang, Hui-Min Huang, Yu-Ji Zhang in Virologica Sinica (2018)

  6. Article

    Open Access

    Joint China-US Call for Employing a Transdisciplinary Approach to Emerging Infectious Diseases

    Jonna A. K. Mazet, Qin Wei, Guo** Zhao, Derek A. T. Cummings in EcoHealth (2015)

  7. Article

    Open Access

    Differential introgression among loci across a hybrid zone of the intermediate horseshoe bat (Rhinolophus affinis)

    Hybrid zones formed by the secondary contact of divergent lineages represent natural laboratories for studying the genetic basis of speciation. Here we tested for patterns of differential introgression among t...

    **uguang Mao, Guangjian Zhu, Libiao Zhang, Shuyi Zhang in BMC Evolutionary Biology (2014)

  8. Article

    Adjuvant effect of CD40 on H5N1 DNA vaccine in mice

    H5N1 viruses cause severe and often fatal disease in humans. DNA vaccines have been shown to provide some protection in many animal models against H5N1 influenza virus infection, but this protection is not com...

    Qin Chen, Guangjian Zhu, Renjie Wang, Junpeng Zhang, Guimei He in Archives of Virology (2014)

  9. Article

    Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

    Whole-genome sequences of two novel SARS-CoV-related bat coronaviruses, in addition to a live isolate of a bat SARS-like coronavirus, are reported; the live isolate can infect human cells using ACE2, providing...

    **ng-Yi Ge, Jia-Lu Li, **ng-Lou Yang, Aleksei A. Chmura, Guangjian Zhu in Nature (2013)

  10. No Access

    Article

    Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer

    Large noncoding RNA HOTAIR, transcribed from the antisense strand of HOXC12, interacts with Polycomb Repressive Complex 2 (PRC2) in the regulation of gene activities. Recent work suggests that it may have effe...

    Lingeng Lu, Guangjian Zhu, Chong Zhang, Qian Deng in Breast Cancer Research and Treatment (2012)

  11. No Access

    Article

    Isolation and characterization of 11 microsatellite loci in Scotophilus kuhlii (Lesser Asiatic Yellow House Bat)

    We used enriched genomic library method to isolate and characterize 11 di-nucleotide microsatellite loci in the Lesser Asiatic Yellow House Bat, Scotophilus kuhlii. The polymorphism of these loci was tested on a ...

    Yanhong Sun, Dongmei Yu, Guangjian Zhu, Xusheng Liu, Shuyi Zhang in Conservation Genetics (2009)