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Open AccessDecoding the RNA viromes in rodent lungs provides new insight into the origin and evolutionary patterns of rodent-borne pathogens in Mainland Southeast Asia
As the largest group of mammalian species, which are also widely distributed all over the world, rodents are the natural reservoirs for many diverse zoonotic viruses. A comprehensive understanding of the core ...
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Open AccessOrigin and cross-species transmission of bat coronaviruses in China
Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of COVID-19. However, the evolution and di...
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Article
Open AccessFabrication of High-Quality and Strain-Relaxed GeSn Microdisks by Integrating Selective Epitaxial Growth and Selective Wet Etching Methods
GeSn is a promising material for the fabrication of on-chip photonic and nanoelectronic devices. Processing techniques dedicated to GeSn have thus been developed, including epitaxy, annealing, ion implantation...
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Open AccessComparative analysis of rodent and small mammal viromes to better understand the wildlife origin of emerging infectious diseases
Rodents represent around 43% of all mammalian species, are widely distributed, and are the natural reservoirs of a diverse group of zoonotic viruses, including hantaviruses, Lassa viruses, and tick-borne encep...
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Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China
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Open AccessJoint China-US Call for Employing a Transdisciplinary Approach to Emerging Infectious Diseases
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Open AccessDifferential introgression among loci across a hybrid zone of the intermediate horseshoe bat (Rhinolophus affinis)
Hybrid zones formed by the secondary contact of divergent lineages represent natural laboratories for studying the genetic basis of speciation. Here we tested for patterns of differential introgression among t...
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Article
Adjuvant effect of CD40 on H5N1 DNA vaccine in mice
H5N1 viruses cause severe and often fatal disease in humans. DNA vaccines have been shown to provide some protection in many animal models against H5N1 influenza virus infection, but this protection is not com...
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Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Whole-genome sequences of two novel SARS-CoV-related bat coronaviruses, in addition to a live isolate of a bat SARS-like coronavirus, are reported; the live isolate can infect human cells using ACE2, providing...
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Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer
Large noncoding RNA HOTAIR, transcribed from the antisense strand of HOXC12, interacts with Polycomb Repressive Complex 2 (PRC2) in the regulation of gene activities. Recent work suggests that it may have effe...
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Article
Isolation and characterization of 11 microsatellite loci in Scotophilus kuhlii (Lesser Asiatic Yellow House Bat)
We used enriched genomic library method to isolate and characterize 11 di-nucleotide microsatellite loci in the Lesser Asiatic Yellow House Bat, Scotophilus kuhlii. The polymorphism of these loci was tested on a ...