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  1. Article

    A novel class of geldanamycin derivatives as HCV replication inhibitors targeting on Hsp90: synthesis, structure–activity relationships and anti-HCV activity in GS4.3 replicon cells

    A novel class of geldanamycin (GA) derivatives as hepatitis C virus (HCV) replication inhibitors has been synthesized and their anti-HCV activities were evaluated in GS4.3 HCV replicon cells. Most of the synth...

    Guang-zhi Shan, Zong-gen Peng, Yu-huan Li, Dong Li in The Journal of Antibiotics (2011)